Odor-Specific Daily Rhythms in the Olfactory Sensitivity and Behavior of <i>Aedes aegypti</i> Mosquitoes
Many biological processes and behaviors in mosquitoes display rhythmic patterns, allowing for fine tuning to cyclic environmental conditions. In mosquitoes, vector-host interactions are primarily mediated by olfactory signals. Previous studies have established that, in the malaria vector <i>An...
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doaj-f1e269ed7d644dca85123e70b9c0a9de2020-11-25T00:15:18ZengMDPI AGInsects2075-44502018-10-019414710.3390/insects9040147insects9040147Odor-Specific Daily Rhythms in the Olfactory Sensitivity and Behavior of <i>Aedes aegypti</i> MosquitoesDiane F. Eilerts0Morgen VanderGiessen1Elizabeth A. Bose2Kyera Broxton3Clément Vinauger4Department of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USADepartment of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USADepartment of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USADepartment of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USADepartment of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USAMany biological processes and behaviors in mosquitoes display rhythmic patterns, allowing for fine tuning to cyclic environmental conditions. In mosquitoes, vector-host interactions are primarily mediated by olfactory signals. Previous studies have established that, in the malaria vector <i>Anopheles gambiae</i>, rhythmic expression of odorant binding proteins and takeout proteins in the antenna resulted in a corresponding rhythm in olfactory sensitivity to relevant host odors. However, it remained unclear how rhythms observed in olfactory sensitivity affect or explain rhythms in behavioral output, which ultimately impacts disease transmission. In order to address this knowledge gap, we quantified and compared patterns in locomotor activity, olfactory sensitivity, and olfactory behaviors in adult female <i>Aedes aegypti</i> mosquitoes. Here, we demonstrate an odorant-specific modulation of olfactory sensitivity in <i>Ae. aegypti</i>, decoupled from rhythms in olfactory behavior. Additionally, behavioral assays performed herein represent the first evidence of a time-dependence of the olfactory activation of behavior in <i>Ae. aegypti</i> mosquitoes. Results suggest that olfactory behavior of <i>Aedes</i> mosquitoes is modulated at both the peripheral (antenna) and central levels. As such, this work serves as a foundation for future studies aimed at further understanding the neural and molecular mechanisms underlying behavioral plasticity.https://www.mdpi.com/2075-4450/9/4/147daily rhythmsbiological rhythmsmosquitoesvectorsolfactionelectrophysiologybehavior |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Diane F. Eilerts Morgen VanderGiessen Elizabeth A. Bose Kyera Broxton Clément Vinauger |
spellingShingle |
Diane F. Eilerts Morgen VanderGiessen Elizabeth A. Bose Kyera Broxton Clément Vinauger Odor-Specific Daily Rhythms in the Olfactory Sensitivity and Behavior of <i>Aedes aegypti</i> Mosquitoes Insects daily rhythms biological rhythms mosquitoes vectors olfaction electrophysiology behavior |
author_facet |
Diane F. Eilerts Morgen VanderGiessen Elizabeth A. Bose Kyera Broxton Clément Vinauger |
author_sort |
Diane F. Eilerts |
title |
Odor-Specific Daily Rhythms in the Olfactory Sensitivity and Behavior of <i>Aedes aegypti</i> Mosquitoes |
title_short |
Odor-Specific Daily Rhythms in the Olfactory Sensitivity and Behavior of <i>Aedes aegypti</i> Mosquitoes |
title_full |
Odor-Specific Daily Rhythms in the Olfactory Sensitivity and Behavior of <i>Aedes aegypti</i> Mosquitoes |
title_fullStr |
Odor-Specific Daily Rhythms in the Olfactory Sensitivity and Behavior of <i>Aedes aegypti</i> Mosquitoes |
title_full_unstemmed |
Odor-Specific Daily Rhythms in the Olfactory Sensitivity and Behavior of <i>Aedes aegypti</i> Mosquitoes |
title_sort |
odor-specific daily rhythms in the olfactory sensitivity and behavior of <i>aedes aegypti</i> mosquitoes |
publisher |
MDPI AG |
series |
Insects |
issn |
2075-4450 |
publishDate |
2018-10-01 |
description |
Many biological processes and behaviors in mosquitoes display rhythmic patterns, allowing for fine tuning to cyclic environmental conditions. In mosquitoes, vector-host interactions are primarily mediated by olfactory signals. Previous studies have established that, in the malaria vector <i>Anopheles gambiae</i>, rhythmic expression of odorant binding proteins and takeout proteins in the antenna resulted in a corresponding rhythm in olfactory sensitivity to relevant host odors. However, it remained unclear how rhythms observed in olfactory sensitivity affect or explain rhythms in behavioral output, which ultimately impacts disease transmission. In order to address this knowledge gap, we quantified and compared patterns in locomotor activity, olfactory sensitivity, and olfactory behaviors in adult female <i>Aedes aegypti</i> mosquitoes. Here, we demonstrate an odorant-specific modulation of olfactory sensitivity in <i>Ae. aegypti</i>, decoupled from rhythms in olfactory behavior. Additionally, behavioral assays performed herein represent the first evidence of a time-dependence of the olfactory activation of behavior in <i>Ae. aegypti</i> mosquitoes. Results suggest that olfactory behavior of <i>Aedes</i> mosquitoes is modulated at both the peripheral (antenna) and central levels. As such, this work serves as a foundation for future studies aimed at further understanding the neural and molecular mechanisms underlying behavioral plasticity. |
topic |
daily rhythms biological rhythms mosquitoes vectors olfaction electrophysiology behavior |
url |
https://www.mdpi.com/2075-4450/9/4/147 |
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