EFFICACY OF INTRA-ARTERIAL LIDOCAINE FOR PAIN CONTROL RESULTING FROM TRANSARTERIAL CHEMOEMBOLIZATION OF HEPATOCELLULAR CARCINOMA
Objective: To assess the efficacy of intra-arterial lidocaine in peri & post-procedural pain control and the dose of narcotic analgesic required in hepatocellular carcinoma patients undergoing transarterial chemoembolization. Study Design: Comparative prospective study. Place and Duration...
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Army Medical College Rawalpindi
2021-06-01
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doaj-f1e2a517e9a44527acb8b109db785b4c2021-10-06T08:56:55ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422021-06-017139101510.51253/pafmj.v71i3.48434843EFFICACY OF INTRA-ARTERIAL LIDOCAINE FOR PAIN CONTROL RESULTING FROM TRANSARTERIAL CHEMOEMBOLIZATION OF HEPATOCELLULAR CARCINOMAGhulam Abbas0Atif Sheraz1Raza Rahim2Armed Forces Institute of Radiology and Imaging /National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Radiology and Imaging /National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Radiology and Imaging /National University of Medical Sciences (NUMS) Rawalpindi PakistanObjective: To assess the efficacy of intra-arterial lidocaine in peri & post-procedural pain control and the dose of narcotic analgesic required in hepatocellular carcinoma patients undergoing transarterial chemoembolization. Study Design: Comparative prospective study. Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, from Jan to Jun 2019. Methodology: A total of 60 patients included in this study where 42 males and 18 were females, age range 45-85 years who underwent transarterial chemoembolization for hepatocellular carcinoma, were included in the study. patients were equally divided into two groups, group a (30 patients) who underwent transarterial chemoembolization, received 60 mg of intraarterial lidocaine each and group b (30 patients) who underwent transarterial chemoembolization, intra-arterial lidocaine was substituted with normal saline.degree of post-procedural pain was assessed using a subjective method (visual analogue scales score) and an objective method (amount of post-procedural analgesics). Results: Average peri-procedure visual analogue scale score was 5.06 in group A patient versus 7.2 for those in group B patients (p=0.037). Post-procedure visual analogue scale score in the group A was 2.7 ± 0.520 and that for group B was 4.2 ± 0.761 (p=0.025). Mean of total dose of nalbuphine in group A was 4.96 ± 0.764 mg versus 8.3 ± 1.34 mg for patients in group B (p=0.036). Average length of post procedure hospital stay was 0.9 ± 0.203 and 1.41 ± 0.373 days for group A and group B respectively (p=0.002). Conclusion: Intra-arterial administration of lidocaine before infusing the embolization particles for transarterial chemoembolization.....................https://pafmj.org/index.php/PAFMJ/article/view/4843hepatocellular carcinoma (hcc)intra-arteriallidocainepain control and pes (post embolization syndrome)trans arterial chemoembolization (tace) & visual analogue score (vas) |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ghulam Abbas Atif Sheraz Raza Rahim |
spellingShingle |
Ghulam Abbas Atif Sheraz Raza Rahim EFFICACY OF INTRA-ARTERIAL LIDOCAINE FOR PAIN CONTROL RESULTING FROM TRANSARTERIAL CHEMOEMBOLIZATION OF HEPATOCELLULAR CARCINOMA Pakistan Armed Forces Medical Journal hepatocellular carcinoma (hcc) intra-arterial lidocaine pain control and pes (post embolization syndrome) trans arterial chemoembolization (tace) & visual analogue score (vas) |
author_facet |
Ghulam Abbas Atif Sheraz Raza Rahim |
author_sort |
Ghulam Abbas |
title |
EFFICACY OF INTRA-ARTERIAL LIDOCAINE FOR PAIN CONTROL RESULTING FROM TRANSARTERIAL CHEMOEMBOLIZATION OF HEPATOCELLULAR CARCINOMA |
title_short |
EFFICACY OF INTRA-ARTERIAL LIDOCAINE FOR PAIN CONTROL RESULTING FROM TRANSARTERIAL CHEMOEMBOLIZATION OF HEPATOCELLULAR CARCINOMA |
title_full |
EFFICACY OF INTRA-ARTERIAL LIDOCAINE FOR PAIN CONTROL RESULTING FROM TRANSARTERIAL CHEMOEMBOLIZATION OF HEPATOCELLULAR CARCINOMA |
title_fullStr |
EFFICACY OF INTRA-ARTERIAL LIDOCAINE FOR PAIN CONTROL RESULTING FROM TRANSARTERIAL CHEMOEMBOLIZATION OF HEPATOCELLULAR CARCINOMA |
title_full_unstemmed |
EFFICACY OF INTRA-ARTERIAL LIDOCAINE FOR PAIN CONTROL RESULTING FROM TRANSARTERIAL CHEMOEMBOLIZATION OF HEPATOCELLULAR CARCINOMA |
title_sort |
efficacy of intra-arterial lidocaine for pain control resulting from transarterial chemoembolization of hepatocellular carcinoma |
publisher |
Army Medical College Rawalpindi |
series |
Pakistan Armed Forces Medical Journal |
issn |
0030-9648 2411-8842 |
publishDate |
2021-06-01 |
description |
Objective: To assess the efficacy of intra-arterial lidocaine in peri & post-procedural pain control and the dose of narcotic analgesic required in hepatocellular carcinoma patients undergoing transarterial chemoembolization.
Study Design: Comparative prospective study.
Place and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, from Jan to Jun 2019.
Methodology: A total of 60 patients included in this study where 42 males and 18 were females, age range 45-85 years who underwent transarterial chemoembolization for hepatocellular carcinoma, were included in the study. patients were equally divided into two groups, group a (30 patients) who underwent transarterial chemoembolization, received 60 mg of intraarterial lidocaine each and group b (30 patients) who underwent transarterial chemoembolization, intra-arterial lidocaine was substituted with normal saline.degree of post-procedural pain was assessed using a subjective method (visual analogue scales score) and an objective method (amount of post-procedural analgesics).
Results: Average peri-procedure visual analogue scale score was 5.06 in group A patient versus 7.2 for those in group B patients (p=0.037). Post-procedure visual analogue scale score in the group A was 2.7 ± 0.520 and that for group B was 4.2 ± 0.761 (p=0.025). Mean of total dose of nalbuphine in group A was 4.96 ± 0.764 mg versus 8.3 ± 1.34 mg for patients in group B (p=0.036). Average length of post procedure hospital stay was 0.9 ± 0.203 and 1.41 ± 0.373 days for group A and group B respectively (p=0.002).
Conclusion: Intra-arterial administration of lidocaine before infusing the embolization particles for transarterial chemoembolization..................... |
topic |
hepatocellular carcinoma (hcc) intra-arterial lidocaine pain control and pes (post embolization syndrome) trans arterial chemoembolization (tace) & visual analogue score (vas) |
url |
https://pafmj.org/index.php/PAFMJ/article/view/4843 |
work_keys_str_mv |
AT ghulamabbas efficacyofintraarteriallidocaineforpaincontrolresultingfromtransarterialchemoembolizationofhepatocellularcarcinoma AT atifsheraz efficacyofintraarteriallidocaineforpaincontrolresultingfromtransarterialchemoembolizationofhepatocellularcarcinoma AT razarahim efficacyofintraarteriallidocaineforpaincontrolresultingfromtransarterialchemoembolizationofhepatocellularcarcinoma |
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