Molecular mechanisms regulating cytotoxic lymphocyte development and function, and their associations to human diseases.

Molecular mechanisms regulating cytotoxic lymphocyte development and function, and their associations to human diseases.

Bibliographic Details
Main Authors:	Konrad eKrzewski, Yenan eBryceson
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-06-01
Series:	Frontiers in Immunology
Subjects:	Perforin NK cells secretory lysosomes Cytotoxicity Immunological Synapse immune therapy
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00279/full

Similar Items

Human NK cell lytic granules and regulation of their exocytosis.
by: Konrad eKrzewski, et al.
Published: (2012-11-01)

Dissecting early mechanism of melanoma cell resistance to cytotoxic T lymphocyte attack
by: Khazen, Roxana
Published: (2016)

Cytotoxic Granule Exocytosis From Human Cytotoxic T Lymphocytes Is Mediated by VAMP7
by: Praneeth Chitirala, et al.
Published: (2019-08-01)

A Deadly Cargo: Gene Repertoire of Cytotoxic Effector Proteins in the <i>Camelidae</i>
by: Ján Futas, et al.
Published: (2021-02-01)

Phenotypic and functional analyses of NK and NKT-like populations during the early stages of chikungunya infection
by: Subrat eThanapati, et al.
Published: (2015-09-01)

Imaging Polarized Secretory Traffic at the Immune Synapse in Living T Lymphocytes
by: Víctor Calvo, et al.
Published: (2018-04-01)

CONTRIBUTION OF DEFECTIVE CYTOTOXICITY TO DEVELOPMENT OF CANINE HEMOPHAGOCYTIC HISTIOCYTIC SARCOMA
by: Neta, Michal
Published: (2001)

Perforinopathy: a spectrum of human immune disease caused by defective perforin delivery or function
by: Joseph A. Trapani, et al.
Published: (2013-12-01)

Extracellular Cystatin F Is Internalised by Cytotoxic T Lymphocytes and Decreases Their Cytotoxicity
by: Mateja Prunk, et al.
Published: (2020-12-01)

THE ACTIVITY OF CYTOTOXIC LYMPHOCYTES IN PATIENTS WITH PREECLAMPSIA
by: A.M. Kurmanova, et al.
Published: (2020-06-01)

Microchip screening platform for single cell assessment of NK cell cytotoxicity
by: Karolin eGuldevall, et al.
Published: (2016-04-01)

NF-κB c-Rel Is Dispensable for the Development but Is Required for the Cytotoxic Function of NK Cells
by: Yorleny Vicioso, et al.
Published: (2021-04-01)

TRP Channels as Interior Designers: Remodeling the Endolysosomal Compartment in Natural Killer Cells
by: Dennis Clement, et al.
Published: (2020-04-01)

Actin Cytoskeleton Straddling the Immunological Synapse between Cytotoxic Lymphocytes and Cancer Cells
by: Hannah Wurzer, et al.
Published: (2019-05-01)

PHENOTYPIC AND FUNCTIONAL CHARACTERISTICS OF MICROVESICLES PRODUCED BY NATURAL KILLER CELLS
by: D. I. Sokolov, et al.
Published: (2019-10-01)

Cx43-Gap Junctions Accumulate at the Cytotoxic Immunological Synapse Enabling Cytotoxic T Lymphocyte Melanoma Cell Killing
by: Francisca Hofmann, et al.
Published: (2019-09-01)

Activation of lymphocyte cytolytic machinery: where we are?
by: Ricciarda eGalandrini, et al.
Published: (2013-11-01)

Effect of asbestos exposure on differentiation and function of cytotoxic T lymphocytes
by: Naoko Kumagai-Takei, et al.
Published: (2020-10-01)

Mechanosensation and Mechanotransduction in Natural Killer Cells
by: Giorgio Santoni, et al.
Published: (2021-07-01)

Mechanisms of Apoptosis Resistance to NK Cell-Mediated Cytotoxicity in Cancer
by: Christian Sordo-Bahamonde, et al.
Published: (2020-05-01)

Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling
by: Hannah Wurzer, et al.
Published: (2021-05-01)

Cytotoxic Granule Trafficking and Fusion in Synaptotagmin7-Deficient Cytotoxic T Lymphocytes
by: Marwa Sleiman, et al.
Published: (2020-05-01)

Inhibition of Perforin-Mediated Neurotoxicity Attenuates Neurological Deficits After Ischemic Stroke
by: Yuhualei Pan, et al.
Published: (2021-06-01)

Candida albicans induces Metabolic Reprogramming in human NK cells and responds to Perforin with a Zinc Depletion Response
by: Daniela eHellwig, et al.
Published: (2016-05-01)

Natural Killer Cell Phenotype and Functionality Affected by Exposure to Extracellular Survivin and Lymphoma-Derived Exosomes
by: Heather R. Ferguson Bennit, et al.
Published: (2021-01-01)

Human immunodeficiency syndromes affecting human natural killer cell cytolytic activity
by: Daniel Denis Billadeau, et al.
Published: (2014-01-01)

ELISPOT Assay for Monitoring Cytotoxic T Lymphocytes (CTL) Activity in Cancer Vaccine Clinical Trials
by: Thomas J. Sayers, et al.
Published: (2012-05-01)

The Role of Tim-3 Receptor in CD8+ T cells Cytotoxicity in Chronic HIV Infection
by: Sakhdari, Ali
Published: (2013)

The Role of Tim-3 Receptor in CD8+ T cells Cytotoxicity in Chronic HIV Infection
by: Sakhdari, Ali
Published: (2013)

NKp46 clusters at the immune synapse and regulates NK cell polarization
by: Uzi eHadad, et al.
Published: (2015-09-01)

"A study on Stress, Depression and NK Cytotoxic Potential in Women with Recurrent Spontaneous Abortion "
by: Alireza alib, et al.
Published: (2006-03-01)

Endometrial Cancer Suppresses CD8+ T Cell-Mediated Cytotoxicity in Postmenopausal Women
by: Mickey V. Patel, et al.
Published: (2021-04-01)

Studying the biology of cytotoxic T lymphocytes in vivo with a fluorescent granzyme B-mTFP knock-in mouse
by: Praneeth Chitirala, et al.
Published: (2020-07-01)

Inhibitory receptor signaling destabilizes immunological synapse formation in primary NK cells
by: Thushara P Abeyweera, et al.
Published: (2013-11-01)

The Complicated Evolutionary Diversification of the Mpeg-1/Perforin-2 Family in Cnidarians
by: Brian M. Walters, et al.
Published: (2020-08-01)

Aberrant hyperactivation of cytotoxic T-cell as a potential determinant of COVID-19 severity
by: Chang Kyung Kang, et al.
Published: (2020-08-01)

Connexin-Mediated Signaling at the Immunological Synapse
by: Andrés Tittarelli, et al.
Published: (2020-05-01)

Advanced Materials and Devices for the Regulation and Study of NK Cells
by: Guillaume Le Saux, et al.
Published: (2019-02-01)

Vδ2 T-Cells Kill ZIKV-Infected Cells by NKG2D-Mediated Cytotoxicity
by: Eleonora Cimini, et al.
Published: (2019-09-01)

Immunological Synapse in the Biology of Chronic Lymphocytic Leukemia
by: DS Badmazhapova, et al.
Published: (2018-10-01)

Cannot write session to /tmp/vufind_sessions/sess_r4pqf4ov3gnkpf1s0thpcnrgnp