Rivaroxaban-induced hemorrhage associated with ABCB1 genetic defect

Rivaroxaban-induced hemorrhage associated with ABCB1 genetic defect

We report a patient who presented a non-ST segment elevation myocardial infarction in the context of severe normocytic hypochromic anemia related to gastrointestinal bleeding, three months after switching anticoagulant from the vitamin K antagonist acenocoumarol to the direct oral anticoagulant riva...

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Bibliographic Details
Main Authors: Kuntheavy Ing Lorenzini, Youssef Daali, Pierre Fontana, Jules Desmeules, Caroline Flora Samer
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Pharmacology
Subjects:
Adverse Drug Reaction
Drug-Drug Interaction
Genetic polymorphism
ABCB1
direct oral anticoagulants
CYP3A4/5
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00494/full

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