Conformational and functional effects induced by D- and L-amino acid epimerization on a single gene encoded peptide from the skin secretion of Hypsiboas punctatus.

Skin secretion of Hypsiboas punctatus is the source of a complex mixture of bioactive compounds where peptides and small proteins prevail, similarly to many other amphibians. Among dozens of molecules isolated from H. punctatus in a proteomic based approach, we report here the structural and functio...

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Bibliographic Details
Main Authors: Mariana T Q de Magalhães, Eder A Barbosa, Maura V Prates, Rodrigo M Verly, Victor Hugo O Munhoz, Ivan E de Araújo, Carlos Bloch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3614549?pdf=render