Pharmacokinetics and tissue distribution of monotropein and deacetyl asperulosidic acid after oral administration of extracts from Morinda officinalis root in rats

Pharmacokinetics and tissue distribution of monotropein and deacetyl asperulosidic acid after oral administration of extracts from Morinda officinalis root in rats

Abstract Background Iridoid glycosides (IGs), including monotropein (MON) and deacetyl asperulosidic acid (DA) as the main ingredients, are the major chemical components in Morinda officinalis How. (MO) root, possessing various pharmacological properties including anti-osteoporosis, anti-inflammatio...

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Main Authors: Yi Shen, Qi Zhang, Yan-bin Wu, Yu-qiong He, Ting Han, Jian-hua Zhang, Liang Zhao, Hsien-yeh Hsu, Hong-tao Song, Bing Lin, Hai-liang Xin, Yun-peng Qi, Qiao-yan Zhang
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Morinda officinalis
Iridoid glycosides
Pharmacokinetics
Tissue distribution
UPLC-MS/MS
Online Access:http://link.springer.com/article/10.1186/s12906-018-2351-1

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