Genomic trajectory in leukemogenesis of myeloproliferative neoplasms: a case report

Genomic trajectory in leukemogenesis of myeloproliferative neoplasms: a case report

Abstract Background We report a patient with Essential Thrombocythemia (ET), subsequently diagnosed with concurrent myeloid and lymphoid leukemia. Generally, the molecular mechanisms underlying leukemic transformation of Philadelphia-negative myeloproliferative neoplasms (Ph-MPN) are poorly understo...

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Bibliographic Details
Main Authors: Yujie Chen, Rafee Talukder, Brian Y. Merritt, Katherine Y. King, Marek Kimmel, Gustavo Rivero, Romina Sosa
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Medical Genomics
Subjects:
Essential thrombocythemia
Leukemia
Clonal evolution
Myeloproliferative neoplasms
Case report
Online Access:https://doi.org/10.1186/s12920-021-00986-z

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