Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San in db/db Mice via Activation of PI3K/Akt and AMPK Pathways

Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San in db/db Mice via Activation of PI3K/Akt and AMPK Pathways

This study was to investigate the anti-diabetic effects and molecular mechanisms of Tang-Kang-Fu-San (TKFS), a traditional Tibetan medicine, in treating type 2 diabetes mellitus of spontaneous diabetic db/db mice. Firstly HPLC fingerprint analysis was performed to gain the features of the chemical c...

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Bibliographic Details
Main Authors: Bailu Duan, Zhongqiu Zhao, Weifang Liao, Hui Xiong, Sisi Liu, Liang Yin, Tiexiang Gao, Zhinan Mei
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Pharmacology
Subjects:
traditional Tibetan medicine
diabetes
Akt
AMPK
db/db mice
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00535/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00535/full

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