Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals

Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals

The aim of the study was to analyze the overall survival (OS) and progression free survival (PFS) of patients with high grade and advanced stage epithelial ovarian cancer (EOC) with at least 60 months of follow-up treated in a single gynecologic oncology institute. We compared primary debulking surg...

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Main Authors: Kobal Borut, Noventa Marco, Cvjeticanin Branko, Barbic Matija, Meglic Leon, Herzog Marusa, Bordi Giulia, Vitagliano Amerigo, Saccardi Carlo, Skof Erik
Format: Article
Language:English
Published: Sciendo 2018-09-01
Series:Radiology and Oncology
Subjects:
epithelial ovarian cancer
advanced stage
primary debulking surgery
interval debulking surgery
neoadjuvant chemotherapy
adjuvant chemotherapy
overall survival
progression free survival
Online Access:https://doi.org/10.2478/raon-2018-0030
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spelling doaj-f254e30f9f9648218e7720343baba6092021-09-05T14:01:18ZengSciendoRadiology and Oncology1581-32072018-09-0152330731910.2478/raon-2018-0030raon-2018-0030Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivalsKobal Borut0Noventa Marco1Cvjeticanin Branko2Barbic Matija3Meglic Leon4Herzog Marusa5Bordi Giulia6Vitagliano Amerigo7Saccardi Carlo8Skof Erik9Division of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, SloveniaDepartment of Woman and Child Health, University of Padua, Padua, ItalyDivision of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, SloveniaDivision of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, SloveniaDivision of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, SloveniaDivision of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, SloveniaDepartment of Gynecology and Obstetrics, University of Insubria, Varese, ItalyDepartment of Woman and Child Health, University of Padua, Padua, ItalyDepartment of Woman and Child Health, University of Padua, Padua, ItalyDepartment of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, SloveniaThe aim of the study was to analyze the overall survival (OS) and progression free survival (PFS) of patients with high grade and advanced stage epithelial ovarian cancer (EOC) with at least 60 months of follow-up treated in a single gynecologic oncology institute. We compared primary debulking surgery (PDS) versus neoadjuvant chemotherapy plus interval debulking surgery (NACT + IDS) stratifying data based on residual disease with the intent to identify the rationale for therapeutic option decision and the role of laparoscopic evaluation of resectability for that intention.https://doi.org/10.2478/raon-2018-0030epithelial ovarian canceradvanced stageprimary debulking surgeryinterval debulking surgeryneoadjuvant chemotherapyadjuvant chemotherapyoverall survivalprogression free survival
collection DOAJ
language English
format Article
sources DOAJ
author Kobal Borut
Noventa Marco
Cvjeticanin Branko
Barbic Matija
Meglic Leon
Herzog Marusa
Bordi Giulia
Vitagliano Amerigo
Saccardi Carlo
Skof Erik
spellingShingle Kobal Borut
Noventa Marco
Cvjeticanin Branko
Barbic Matija
Meglic Leon
Herzog Marusa
Bordi Giulia
Vitagliano Amerigo
Saccardi Carlo
Skof Erik
Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals
Radiology and Oncology
epithelial ovarian cancer
advanced stage
primary debulking surgery
interval debulking surgery
neoadjuvant chemotherapy
adjuvant chemotherapy
overall survival
progression free survival
author_facet Kobal Borut
Noventa Marco
Cvjeticanin Branko
Barbic Matija
Meglic Leon
Herzog Marusa
Bordi Giulia
Vitagliano Amerigo
Saccardi Carlo
Skof Erik
author_sort Kobal Borut
title Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals
title_short Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals
title_full Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals
title_fullStr Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals
title_full_unstemmed Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals
title_sort primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals
publisher Sciendo
series Radiology and Oncology
issn 1581-3207
publishDate 2018-09-01
description The aim of the study was to analyze the overall survival (OS) and progression free survival (PFS) of patients with high grade and advanced stage epithelial ovarian cancer (EOC) with at least 60 months of follow-up treated in a single gynecologic oncology institute. We compared primary debulking surgery (PDS) versus neoadjuvant chemotherapy plus interval debulking surgery (NACT + IDS) stratifying data based on residual disease with the intent to identify the rationale for therapeutic option decision and the role of laparoscopic evaluation of resectability for that intention.
topic epithelial ovarian cancer
advanced stage
primary debulking surgery
interval debulking surgery
neoadjuvant chemotherapy
adjuvant chemotherapy
overall survival
progression free survival
url https://doi.org/10.2478/raon-2018-0030
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