Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals
The aim of the study was to analyze the overall survival (OS) and progression free survival (PFS) of patients with high grade and advanced stage epithelial ovarian cancer (EOC) with at least 60 months of follow-up treated in a single gynecologic oncology institute. We compared primary debulking surg...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Sciendo
2018-09-01
|
Series: | Radiology and Oncology |
Subjects: | |
Online Access: | https://doi.org/10.2478/raon-2018-0030 |
id |
doaj-f254e30f9f9648218e7720343baba609 |
---|---|
record_format |
Article |
spelling |
doaj-f254e30f9f9648218e7720343baba6092021-09-05T14:01:18ZengSciendoRadiology and Oncology1581-32072018-09-0152330731910.2478/raon-2018-0030raon-2018-0030Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivalsKobal Borut0Noventa Marco1Cvjeticanin Branko2Barbic Matija3Meglic Leon4Herzog Marusa5Bordi Giulia6Vitagliano Amerigo7Saccardi Carlo8Skof Erik9Division of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, SloveniaDepartment of Woman and Child Health, University of Padua, Padua, ItalyDivision of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, SloveniaDivision of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, SloveniaDivision of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, SloveniaDivision of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, SloveniaDepartment of Gynecology and Obstetrics, University of Insubria, Varese, ItalyDepartment of Woman and Child Health, University of Padua, Padua, ItalyDepartment of Woman and Child Health, University of Padua, Padua, ItalyDepartment of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, SloveniaThe aim of the study was to analyze the overall survival (OS) and progression free survival (PFS) of patients with high grade and advanced stage epithelial ovarian cancer (EOC) with at least 60 months of follow-up treated in a single gynecologic oncology institute. We compared primary debulking surgery (PDS) versus neoadjuvant chemotherapy plus interval debulking surgery (NACT + IDS) stratifying data based on residual disease with the intent to identify the rationale for therapeutic option decision and the role of laparoscopic evaluation of resectability for that intention.https://doi.org/10.2478/raon-2018-0030epithelial ovarian canceradvanced stageprimary debulking surgeryinterval debulking surgeryneoadjuvant chemotherapyadjuvant chemotherapyoverall survivalprogression free survival |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kobal Borut Noventa Marco Cvjeticanin Branko Barbic Matija Meglic Leon Herzog Marusa Bordi Giulia Vitagliano Amerigo Saccardi Carlo Skof Erik |
spellingShingle |
Kobal Borut Noventa Marco Cvjeticanin Branko Barbic Matija Meglic Leon Herzog Marusa Bordi Giulia Vitagliano Amerigo Saccardi Carlo Skof Erik Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals Radiology and Oncology epithelial ovarian cancer advanced stage primary debulking surgery interval debulking surgery neoadjuvant chemotherapy adjuvant chemotherapy overall survival progression free survival |
author_facet |
Kobal Borut Noventa Marco Cvjeticanin Branko Barbic Matija Meglic Leon Herzog Marusa Bordi Giulia Vitagliano Amerigo Saccardi Carlo Skof Erik |
author_sort |
Kobal Borut |
title |
Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals |
title_short |
Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals |
title_full |
Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals |
title_fullStr |
Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals |
title_full_unstemmed |
Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals |
title_sort |
primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals |
publisher |
Sciendo |
series |
Radiology and Oncology |
issn |
1581-3207 |
publishDate |
2018-09-01 |
description |
The aim of the study was to analyze the overall survival (OS) and progression free survival (PFS) of patients with high grade and advanced stage epithelial ovarian cancer (EOC) with at least 60 months of follow-up treated in a single gynecologic oncology institute. We compared primary debulking surgery (PDS) versus neoadjuvant chemotherapy plus interval debulking surgery (NACT + IDS) stratifying data based on residual disease with the intent to identify the rationale for therapeutic option decision and the role of laparoscopic evaluation of resectability for that intention. |
topic |
epithelial ovarian cancer advanced stage primary debulking surgery interval debulking surgery neoadjuvant chemotherapy adjuvant chemotherapy overall survival progression free survival |
url |
https://doi.org/10.2478/raon-2018-0030 |
work_keys_str_mv |
AT kobalborut primarydebulkingsurgeryversusprimaryneoadjuvantchemotherapyforhighgradeadvancedstageovariancancercomparisonofsurvivals AT noventamarco primarydebulkingsurgeryversusprimaryneoadjuvantchemotherapyforhighgradeadvancedstageovariancancercomparisonofsurvivals AT cvjeticaninbranko primarydebulkingsurgeryversusprimaryneoadjuvantchemotherapyforhighgradeadvancedstageovariancancercomparisonofsurvivals AT barbicmatija primarydebulkingsurgeryversusprimaryneoadjuvantchemotherapyforhighgradeadvancedstageovariancancercomparisonofsurvivals AT meglicleon primarydebulkingsurgeryversusprimaryneoadjuvantchemotherapyforhighgradeadvancedstageovariancancercomparisonofsurvivals AT herzogmarusa primarydebulkingsurgeryversusprimaryneoadjuvantchemotherapyforhighgradeadvancedstageovariancancercomparisonofsurvivals AT bordigiulia primarydebulkingsurgeryversusprimaryneoadjuvantchemotherapyforhighgradeadvancedstageovariancancercomparisonofsurvivals AT vitaglianoamerigo primarydebulkingsurgeryversusprimaryneoadjuvantchemotherapyforhighgradeadvancedstageovariancancercomparisonofsurvivals AT saccardicarlo primarydebulkingsurgeryversusprimaryneoadjuvantchemotherapyforhighgradeadvancedstageovariancancercomparisonofsurvivals AT skoferik primarydebulkingsurgeryversusprimaryneoadjuvantchemotherapyforhighgradeadvancedstageovariancancercomparisonofsurvivals |
_version_ |
1717810474864607232 |