Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia

Behçet’s disease is a multi-systemic vasculitis which is characterized by recurrent oral and genital ulceration with positive pathergy test. These features may also be seen in various hematological malignancies. In patients with leukemia who present with Behçet’s disease-like features, it is often d...

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Main Authors: Ashish Sharma, Mohammad Ali, Shruti Chauhan, Smita Singh, Vivek Arya
Format: Article
Language:English
Published: Termedia Publishing House 2019-06-01
Series:Rheumatology
Subjects:
Online Access:https://www.termedia.pl/Acute-myeloid-leukemia-in-a-young-male-patient-with-Behcet-s-disease-presenting-with-febrile-neutropenia,18,37114,1,1.html
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spelling doaj-f25f895372b34a74a7bfcf45eec4a0f02020-11-25T03:11:19ZengTermedia Publishing HouseRheumatology0034-62332084-98342019-06-0157317818110.5114/reum.2019.8643037114Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropeniaAshish SharmaMohammad AliShruti ChauhanSmita SinghVivek AryaBehçet’s disease is a multi-systemic vasculitis which is characterized by recurrent oral and genital ulceration with positive pathergy test. These features may also be seen in various hematological malignancies. In patients with leukemia who present with Behçet’s disease-like features, it is often difficult to ascertain whether the clinical manifestations are due to leukemia, or there is co-existing Behçet’s disease too. The authors report an Indian farmer who presented with clinical features suggestive of Behçet’s disease with profound neutropenia. On bone marrow examination he was found to have acute monocytic leukemia (AML-M5). Chemotherapy for leukemia did not relieve his oral and genital ulcers, for which glucocorticoids and colchicine had to be given. So the patient had co-existence of Behçet’s disease along with AML-M5, which has never been reported in the literature before.https://www.termedia.pl/Acute-myeloid-leukemia-in-a-young-male-patient-with-Behcet-s-disease-presenting-with-febrile-neutropenia,18,37114,1,1.htmlacute myeloid leukemia neutropenia behçet’s disease pathergy reaction
collection DOAJ
language English
format Article
sources DOAJ
author Ashish Sharma
Mohammad Ali
Shruti Chauhan
Smita Singh
Vivek Arya
spellingShingle Ashish Sharma
Mohammad Ali
Shruti Chauhan
Smita Singh
Vivek Arya
Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia
Rheumatology
acute myeloid leukemia
neutropenia
behçet’s disease
pathergy reaction
author_facet Ashish Sharma
Mohammad Ali
Shruti Chauhan
Smita Singh
Vivek Arya
author_sort Ashish Sharma
title Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia
title_short Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia
title_full Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia
title_fullStr Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia
title_full_unstemmed Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia
title_sort acute myeloid leukemia in a young male patient with behçet’s disease presenting with febrile neutropenia
publisher Termedia Publishing House
series Rheumatology
issn 0034-6233
2084-9834
publishDate 2019-06-01
description Behçet’s disease is a multi-systemic vasculitis which is characterized by recurrent oral and genital ulceration with positive pathergy test. These features may also be seen in various hematological malignancies. In patients with leukemia who present with Behçet’s disease-like features, it is often difficult to ascertain whether the clinical manifestations are due to leukemia, or there is co-existing Behçet’s disease too. The authors report an Indian farmer who presented with clinical features suggestive of Behçet’s disease with profound neutropenia. On bone marrow examination he was found to have acute monocytic leukemia (AML-M5). Chemotherapy for leukemia did not relieve his oral and genital ulcers, for which glucocorticoids and colchicine had to be given. So the patient had co-existence of Behçet’s disease along with AML-M5, which has never been reported in the literature before.
topic acute myeloid leukemia
neutropenia
behçet’s disease
pathergy reaction
url https://www.termedia.pl/Acute-myeloid-leukemia-in-a-young-male-patient-with-Behcet-s-disease-presenting-with-febrile-neutropenia,18,37114,1,1.html
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