Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia
Behçet’s disease is a multi-systemic vasculitis which is characterized by recurrent oral and genital ulceration with positive pathergy test. These features may also be seen in various hematological malignancies. In patients with leukemia who present with Behçet’s disease-like features, it is often d...
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doaj-f25f895372b34a74a7bfcf45eec4a0f02020-11-25T03:11:19ZengTermedia Publishing HouseRheumatology0034-62332084-98342019-06-0157317818110.5114/reum.2019.8643037114Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropeniaAshish SharmaMohammad AliShruti ChauhanSmita SinghVivek AryaBehçet’s disease is a multi-systemic vasculitis which is characterized by recurrent oral and genital ulceration with positive pathergy test. These features may also be seen in various hematological malignancies. In patients with leukemia who present with Behçet’s disease-like features, it is often difficult to ascertain whether the clinical manifestations are due to leukemia, or there is co-existing Behçet’s disease too. The authors report an Indian farmer who presented with clinical features suggestive of Behçet’s disease with profound neutropenia. On bone marrow examination he was found to have acute monocytic leukemia (AML-M5). Chemotherapy for leukemia did not relieve his oral and genital ulcers, for which glucocorticoids and colchicine had to be given. So the patient had co-existence of Behçet’s disease along with AML-M5, which has never been reported in the literature before.https://www.termedia.pl/Acute-myeloid-leukemia-in-a-young-male-patient-with-Behcet-s-disease-presenting-with-febrile-neutropenia,18,37114,1,1.htmlacute myeloid leukemia neutropenia behçet’s disease pathergy reaction |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ashish Sharma Mohammad Ali Shruti Chauhan Smita Singh Vivek Arya |
spellingShingle |
Ashish Sharma Mohammad Ali Shruti Chauhan Smita Singh Vivek Arya Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia Rheumatology acute myeloid leukemia neutropenia behçet’s disease pathergy reaction |
author_facet |
Ashish Sharma Mohammad Ali Shruti Chauhan Smita Singh Vivek Arya |
author_sort |
Ashish Sharma |
title |
Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia |
title_short |
Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia |
title_full |
Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia |
title_fullStr |
Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia |
title_full_unstemmed |
Acute myeloid leukemia in a young male patient with Behçet’s disease presenting with febrile neutropenia |
title_sort |
acute myeloid leukemia in a young male patient with behçet’s disease presenting with febrile neutropenia |
publisher |
Termedia Publishing House |
series |
Rheumatology |
issn |
0034-6233 2084-9834 |
publishDate |
2019-06-01 |
description |
Behçet’s disease is a multi-systemic vasculitis which is characterized by recurrent oral and genital ulceration with positive pathergy test. These features may also be seen in various hematological malignancies. In patients with leukemia who present with Behçet’s disease-like features, it is often difficult to ascertain whether the clinical manifestations are due to leukemia, or there is co-existing Behçet’s disease too. The authors report an Indian farmer who presented with clinical features suggestive of Behçet’s disease with profound neutropenia. On bone marrow examination he was found to have acute monocytic leukemia (AML-M5). Chemotherapy for leukemia did not relieve his oral and genital ulcers, for which glucocorticoids and colchicine had to be given. So the patient had co-existence of Behçet’s disease along with AML-M5, which has never been reported in the literature before. |
topic |
acute myeloid leukemia neutropenia behçet’s disease pathergy reaction |
url |
https://www.termedia.pl/Acute-myeloid-leukemia-in-a-young-male-patient-with-Behcet-s-disease-presenting-with-febrile-neutropenia,18,37114,1,1.html |
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