A Comparative Reverse Docking Strategy to Identify Potential Antineoplastic Targets of Tea Functional Components and Binding Mode

A Comparative Reverse Docking Strategy to Identify Potential Antineoplastic Targets of Tea Functional Components and Binding Mode

The main functional components of green tea, such as epigallocatechin gallate (EGCG), epigallocatechin (EGC), epicatechin gallate (ECG) and epicatechin (EC), are found to have a broad antineoplastic activity. The discovery of their targets plays an important role in revealing the antineoplastic mech...

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Bibliographic Details
Main Authors: Rong Zheng, Tuan-sheng Chen, Tun Lu
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:International Journal of Molecular Sciences
Subjects:
tea polyphenols
reverse docking
target protein
binding mode
virtual screening
Online Access:http://www.mdpi.com/1422-0067/12/8/5200/

Internet

http://www.mdpi.com/1422-0067/12/8/5200/

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