Prognostic value of rise in neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in predicting the mortality in pediatric intensive care

• Main Authors: Siby Mathews, Aswathy Rajan, Santosh T Soans
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2018-01-01
• Series: Journal of Pediatric Critical Care
• Subjects: nlr; plr; mortality indicator; pediatric intensive care; prognostic indicator
• Online Access: http://www.jpcc.org.in/article.asp?issn=2349-6592;year=2018;volume=5;issue=8;spage=71;epage=71;aulast=Mathews;type=0
• ISSN: 2349-6592; 2455-7099

Objective: To assess the prognostic value of rise in NLR and PLR in pediatric intensive care as markers of mortality. Materials and methods: A retrospective study based on 2 year data from HIMS and G-HEALTH data systems of AJ Institute of Medical Science, of all patients admitted to PICU after excluding those in whom all the study parameters were not retrievable. NLR and PLR ratios were determined and compared to PELOD 2 using SPSS version 17.0 Results: The demographic data was matched, the median NLR rise was 0.175 (IQR 1.714) while for PLR rise was 4.623 (IQR 85.533). PELOD 2 predicted mortality in 72.2% of the patients, while NLR increase predicted in 64.11% and PLR increase in 77.77%. A decreasing trend in NLR and PLR were both closely related to lesser length of stay in hospital and better survival. Conclusion: The study gives an insight into the fact that simple and inexpensive markers such as rise in NLR and PLR helps in predicting the mortality in the pediatric intensive care which is comparable to PELOD scoring.