HEDGEHOG/GLI Modulates the PRR11-SKA2 Bidirectional Transcription Unit in Lung Squamous Cell Carcinomas

HEDGEHOG/GLI Modulates the PRR11-SKA2 Bidirectional Transcription Unit in Lung Squamous Cell Carcinomas

We previously demonstrated that proline-rich protein 11 (PRR11) and spindle and kinetochore associated 2 (SKA2) constituted a head-to-head gene pair driven by a prototypical bidirectional promoter. This gene pair synergistically promoted the development of non-small cell lung cancer. However, the si...

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Bibliographic Details
Main Authors: Yiyun Sun, Dandan Xu, Chundong Zhang, Yitao Wang, Lian Zhang, Deqian Qiao, Youquan Bu, Ying Zhang
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Genes
Subjects:
hedgehog
GLI
PRR11
SKA2
lung squamous cell carcinoma
Online Access:https://www.mdpi.com/2073-4425/12/1/120

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