Oral Spermine Supplementation in Gestated Rabbit: A Study on Villi Height of Immature Intestines
Introduction: Immature intestines are the major problem in prematurity. Postnatal oral spermine has been shown in studies to improve intestinal maturation in rats and piglets. This study aimed to find out the efficacy of spermine in rabbits during gestation.Method: An experimental study was done in...
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Frontiers Media S.A.
2021-09-01
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doaj-f2980e53c3dd40949041efa222b0deaf2021-09-09T14:08:47ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2021-09-01810.3389/fsurg.2021.721560721560Oral Spermine Supplementation in Gestated Rabbit: A Study on Villi Height of Immature IntestinesRiana Pauline TambaYefta MoenadjatIntroduction: Immature intestines are the major problem in prematurity. Postnatal oral spermine has been shown in studies to improve intestinal maturation in rats and piglets. This study aimed to find out the efficacy of spermine in rabbits during gestation.Method: An experimental study was done in an unblinded, randomized manner on those treated with and without spermine administration. A morphological examination of hematoxylin–eosin-stained villi was performed under a light microscope with a focus on villi height. Data were subjected to analysis.Results: The median of the spermine-treated group was found to be higher at 24, 26, and 28 days than the non-spermine group, but was not significantly different.Conclusion: Oral spermine supplementation during gestation might improve intestinal villi height in immature rabbit intestines.https://www.frontiersin.org/articles/10.3389/fsurg.2021.721560/fullsperminerabbitgestationimmature intestinesvilli height |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Riana Pauline Tamba Yefta Moenadjat |
spellingShingle |
Riana Pauline Tamba Yefta Moenadjat Oral Spermine Supplementation in Gestated Rabbit: A Study on Villi Height of Immature Intestines Frontiers in Surgery spermine rabbit gestation immature intestines villi height |
author_facet |
Riana Pauline Tamba Yefta Moenadjat |
author_sort |
Riana Pauline Tamba |
title |
Oral Spermine Supplementation in Gestated Rabbit: A Study on Villi Height of Immature Intestines |
title_short |
Oral Spermine Supplementation in Gestated Rabbit: A Study on Villi Height of Immature Intestines |
title_full |
Oral Spermine Supplementation in Gestated Rabbit: A Study on Villi Height of Immature Intestines |
title_fullStr |
Oral Spermine Supplementation in Gestated Rabbit: A Study on Villi Height of Immature Intestines |
title_full_unstemmed |
Oral Spermine Supplementation in Gestated Rabbit: A Study on Villi Height of Immature Intestines |
title_sort |
oral spermine supplementation in gestated rabbit: a study on villi height of immature intestines |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Surgery |
issn |
2296-875X |
publishDate |
2021-09-01 |
description |
Introduction: Immature intestines are the major problem in prematurity. Postnatal oral spermine has been shown in studies to improve intestinal maturation in rats and piglets. This study aimed to find out the efficacy of spermine in rabbits during gestation.Method: An experimental study was done in an unblinded, randomized manner on those treated with and without spermine administration. A morphological examination of hematoxylin–eosin-stained villi was performed under a light microscope with a focus on villi height. Data were subjected to analysis.Results: The median of the spermine-treated group was found to be higher at 24, 26, and 28 days than the non-spermine group, but was not significantly different.Conclusion: Oral spermine supplementation during gestation might improve intestinal villi height in immature rabbit intestines. |
topic |
spermine rabbit gestation immature intestines villi height |
url |
https://www.frontiersin.org/articles/10.3389/fsurg.2021.721560/full |
work_keys_str_mv |
AT rianapaulinetamba oralsperminesupplementationingestatedrabbitastudyonvilliheightofimmatureintestines AT yeftamoenadjat oralsperminesupplementationingestatedrabbitastudyonvilliheightofimmatureintestines |
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1717759068770140160 |