Several domains from VAR2CSA can induce <it>Plasmodium falciparum </it>adhesion-blocking antibodies

Several domains from VAR2CSA can induce <it>Plasmodium falciparum </it>adhesion-blocking antibodies

<p>Abstract</p> <p>Background</p> <p>Malaria caused by <it>Plasmodium falciparum </it>can result in several different syndromes with severe clinical consequences for the about 200 million individuals infected each year. During pregnancy, women living in ende...

Full description

Bibliographic Details
Main Authors:	Theander Thor G, Manczak Tom, Andersen Gorm, Dahlbäck Madeleine, Pinto Vera V, Ditlev Sisse B, Resende Mafalda, Salanti Ali, Nielsen Morten A
Format:	Article
Language:	English
Published:	BMC 2010-01-01
Series:	Malaria Journal
Online Access:	http://www.malariajournal.com/content/9/1/11

Similar Items

Identification of glycosaminoglycan binding regions in the <it>Plasmodium falciparum </it>encoded placental sequestration ligand, VAR2CSA
by: Theander Thor G, et al.
Published: (2008-06-01)

Differential induction of functional IgG using the Plasmodium falciparum placental malaria vaccine candidate VAR2CSA.
by: Vera V Pinto, et al.
Published: (2011-03-01)

Structural insight into epitopes in the pregnancy-associated malaria protein VAR2CSA.
by: Pernille Andersen, et al.
Published: (2008-02-01)

Identification and characterization of B-cell epitopes in the DBL4ε domain of VAR2CSA.
by: Sisse B Ditlev, et al.
Published: (2012-01-01)

Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration.
by: Madeleine Dahlbäck, et al.
Published: (2006-11-01)

Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.
by: Sisse B Ditlev, et al.
Published: (2014-01-01)

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA.
by: Susan Thrane, et al.
Published: (2015-01-01)

Changes in <it>var </it>gene mRNA levels during erythrocytic development in two phenotypically distinct <it>Plasmodium falciparum </it>parasites
by: Theander Thor G, et al.
Published: (2007-06-01)

Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1.
by: Marina Ayres Pereira, et al.
Published: (2016-08-01)

The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine.
by: Morten A Nielsen, et al.
Published: (2015-01-01)

The kinetics of antibody binding to <it>Plasmodium falciparum </it>VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
by: Arnot David E, et al.
Published: (2010-04-01)

VAR2CSA signatures of high Plasmodium falciparum parasitemia in the placenta.
by: Eduard Rovira-Vallbona, et al.
Published: (2013-01-01)

Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates.
by: Adam F Sander, et al.
Published: (2009-08-01)

Default Pathway of var2csa switching and translational repression in Plasmodium falciparum.
by: Bobo W Mok, et al.
Published: (2008-01-01)

VAR2CSA Serology to Detect Plasmodium falciparum Transmission Patterns in Pregnancy
by: Ana Maria Fonseca, et al.
Published: (2019-10-01)

Plasmodium falciparum genetic variation of var2csa in the Democratic Republic of the Congo
by: Robert Verity, et al.
Published: (2018-01-01)

Characterization of VAR2CSA-deficient <it>Plasmodium falciparum</it>-infected erythrocytes selected for adhesion to the BeWo placental cell line
by: Brown Graham V, et al.
Published: (2008-03-01)

Differential evolution of anti-VAR2CSA- IgG3 in primigravidae and multigravidae pregnant women infected by <it>Plasmodium falciparum</it>
by: Sow Sokhna, et al.
Published: (2008-01-01)

Sub-grouping of <it>Plasmodium falciparum </it>3D7 <it>var </it>genes based on sequence analysis of coding and non-coding regions
by: Arnot David E, et al.
Published: (2003-09-01)

VAR2CSA-Mediated Host Defense Evasion of Plasmodium falciparum Infected Erythrocytes in Placental Malaria
by: Alice Tomlinson, et al.
Published: (2021-02-01)

The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner
by: Mette Ø. Agerbæk, et al.
Published: (2018-08-01)

A new method for sequencing the hypervariable Plasmodium falciparum gene var2csa from clinical samples
by: Antoine Dara, et al.
Published: (2017-08-01)

Antibodies to Cryptic Epitopes in Distant Homologues Underpin a Mechanism of Heterologous Immunity between Plasmodium vivax PvDBP and Plasmodium falciparum VAR2CSA
by: Catherine J. Mitran, et al.
Published: (2019-10-01)

Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA.
by: Dominique Dorin-Semblat, et al.
Published: (2019-06-01)

An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria.
by: Borko Amulic, et al.
Published: (2009-01-01)

Plasmodium falciparum VAR2CSA-Specific IgG Subclass Responses Reflect Protection Against Low Birth Weight and Pregnancy-Associated Malaria
by: Bernard Tornyigah, et al.
Published: (2021-04-01)

Insight into antigenic diversity of VAR2CSA-DBL5ε domain from multiple Plasmodium falciparum placental isolates.
by: Sédami Gnidehou, et al.
Published: (2010-10-01)

CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for var2csa Gene Activation or Silencing in Plasmodium falciparum
by: Jessica M. Bryant, et al.
Published: (2017-07-01)

A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in <it>Plasmodium falciparum </it>infected erythrocytes
by: Arnot David E, et al.
Published: (2008-06-01)

Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer.
by: Thomas S Rask, et al.
Published: (2010-09-01)

Antibody levels to recombinant VAR2CSA domains vary with Plasmodium falciparum parasitaemia, gestational age, and gravidity, but do not predict pregnancy outcomes
by: Michal Fried, et al.
Published: (2018-03-01)

Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression.
by: Nicaise Tuikue Ndam, et al.
Published: (2008-03-01)

Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA.
by: Justin Doritchamou, et al.
Published: (2015-01-01)

Analyses of Plasmodium falciparum var genes
by: Ward, C. P.
Published: (2001)

Analysis of Plasmodium falciparum var genes
by: Ward, Christopher Patrick
Published: (2000)

Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding
by: Kaituo Wang, et al.
Published: (2021-05-01)

Disruption of var2csa gene impairs placental malaria associated adhesion phenotype.
by: Nicola K Viebig, et al.
Published: (2007-09-01)

CD36 selection of 3D7 <it>Plasmodium falciparum </it>associated with severe childhood malaria results in reduced VAR4 expression
by: Hviid Lars, et al.
Published: (2008-10-01)

Expression of <it>Plasmodium falciparum </it>erythrocyte membrane protein 1 in experimentally infected humans
by: Theander Thor G, et al.
Published: (2005-04-01)

Plasmodium falciparum variability and immune evasion proceed from antigenicity of consensus sequences from DBL6ε; generalization to all DBL from VAR2CSA.
by: Philippe Deloron, et al.
Published: (2013-01-01)

Cannot write session to /tmp/vufind_sessions/sess_ndtkr6ko87i856teq1v0neap56