Local Usage of Nigella sativa Oil as an Innovative Method to Attenuate Primary Dysmenorrhea: A Randomized Double-blind Clinical Trial
Objectives: We sought to determine the effect of topical application of Nigella sativa (black seed) oil, on the primary dysmenorrhea intensity. Methods: We conducted a randomized, double-blind clinical trial on 124 female students, 18–22 years old, living in the dormitories of Sabzevar Universities....
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Oman Medical Specialty Board
2020-09-01
|
Series: | Oman Medical Journal |
Subjects: | |
Online Access: | http://omjournal.org/articleDetails.aspx?coType=1&aId=2733 |
id |
doaj-f2c1a8dca1674e6293fc3666395939a3 |
---|---|
record_format |
Article |
spelling |
doaj-f2c1a8dca1674e6293fc3666395939a32020-11-25T03:56:55ZengOman Medical Specialty BoardOman Medical Journal1999-768X2070-52042020-09-01355e167e16710.5001/omj.2020.109Local Usage of Nigella sativa Oil as an Innovative Method to Attenuate Primary Dysmenorrhea: A Randomized Double-blind Clinical TrialEzat Samadipour0Mohammad Hassan Rakhshani1Akram Kooshki2Bahareh Amin3Department of Nursing, Sabzevar University of Medical Sciences, Sabzevar, IranDepartment of Statistic, Sabzevar University of Medical Sciences, Sabzevar, IranNon-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, IranCellular and Molecular Research Center, Department of Physiology and Pharmacology, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, IranObjectives: We sought to determine the effect of topical application of Nigella sativa (black seed) oil, on the primary dysmenorrhea intensity. Methods: We conducted a randomized, double-blind clinical trial on 124 female students, 18–22 years old, living in the dormitories of Sabzevar Universities. After a primary assessment, participants were randomly divided into two groups. The first group rubbed two drops of N. sativa oil, and the second group rubbed liquid olive oil, as the placebo. Massage was performed on the fontanel lobe 3, at night, three days before menstruation, for eight consecutive days (about five days after menses). This procedure was repeated for three menstrual cycles. After three cycles, pain severity was measured by the visual analog scale. Data analysis was carried out using the Mann-Whitney U test and analysis of covariance (ANCOVA). Results: This study was conducted on 124 female students. The mean age of students, mean age of first menarche, body mass index, and pain severity were not significantly different in the two groups (p > 0.050). No adverse effects were observed during the study. The results of ANCOVA showed that pain intensity in N. sativa oil group was significantly decreased compared to that of the placebo group (0.6 score; p < 0.050). Conclusions: N. sativa could be a promising, safe, and easily available analgesic supplement in women suffering from primary dysmenorrhea.http://omjournal.org/articleDetails.aspx?coType=1&aId=2733dysmenorrheamenstruationnigella sativamassage |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ezat Samadipour Mohammad Hassan Rakhshani Akram Kooshki Bahareh Amin |
spellingShingle |
Ezat Samadipour Mohammad Hassan Rakhshani Akram Kooshki Bahareh Amin Local Usage of Nigella sativa Oil as an Innovative Method to Attenuate Primary Dysmenorrhea: A Randomized Double-blind Clinical Trial Oman Medical Journal dysmenorrhea menstruation nigella sativa massage |
author_facet |
Ezat Samadipour Mohammad Hassan Rakhshani Akram Kooshki Bahareh Amin |
author_sort |
Ezat Samadipour |
title |
Local Usage of Nigella sativa Oil as an Innovative Method to Attenuate Primary Dysmenorrhea: A Randomized Double-blind Clinical Trial |
title_short |
Local Usage of Nigella sativa Oil as an Innovative Method to Attenuate Primary Dysmenorrhea: A Randomized Double-blind Clinical Trial |
title_full |
Local Usage of Nigella sativa Oil as an Innovative Method to Attenuate Primary Dysmenorrhea: A Randomized Double-blind Clinical Trial |
title_fullStr |
Local Usage of Nigella sativa Oil as an Innovative Method to Attenuate Primary Dysmenorrhea: A Randomized Double-blind Clinical Trial |
title_full_unstemmed |
Local Usage of Nigella sativa Oil as an Innovative Method to Attenuate Primary Dysmenorrhea: A Randomized Double-blind Clinical Trial |
title_sort |
local usage of nigella sativa oil as an innovative method to attenuate primary dysmenorrhea: a randomized double-blind clinical trial |
publisher |
Oman Medical Specialty Board |
series |
Oman Medical Journal |
issn |
1999-768X 2070-5204 |
publishDate |
2020-09-01 |
description |
Objectives: We sought to determine the effect of topical application of Nigella sativa (black seed) oil, on the primary dysmenorrhea intensity. Methods: We conducted a randomized, double-blind clinical trial on 124 female students, 18–22 years old, living in the dormitories of Sabzevar Universities. After a primary assessment, participants were randomly divided into two groups. The first group rubbed two drops of N. sativa oil, and the second group rubbed liquid olive oil, as the placebo. Massage was performed on the fontanel lobe 3, at
night, three days before menstruation, for eight consecutive days (about five days after menses). This procedure was repeated for three menstrual cycles. After three cycles, pain severity was measured by the visual analog scale. Data analysis was carried out using the
Mann-Whitney U test and analysis of covariance (ANCOVA). Results: This study was conducted on 124 female students. The mean age of students, mean age of first menarche, body mass index, and pain severity were not significantly different in the two groups (p > 0.050). No adverse effects were observed during the study. The results of ANCOVA showed that pain intensity in N. sativa oil group was significantly decreased compared to that of the placebo group (0.6 score; p < 0.050). Conclusions: N. sativa could be a promising, safe, and easily available analgesic supplement in women suffering from primary dysmenorrhea. |
topic |
dysmenorrhea menstruation nigella sativa massage |
url |
http://omjournal.org/articleDetails.aspx?coType=1&aId=2733 |
work_keys_str_mv |
AT ezatsamadipour localusageofnigellasativaoilasaninnovativemethodtoattenuateprimarydysmenorrheaarandomizeddoubleblindclinicaltrial AT mohammadhassanrakhshani localusageofnigellasativaoilasaninnovativemethodtoattenuateprimarydysmenorrheaarandomizeddoubleblindclinicaltrial AT akramkooshki localusageofnigellasativaoilasaninnovativemethodtoattenuateprimarydysmenorrheaarandomizeddoubleblindclinicaltrial AT baharehamin localusageofnigellasativaoilasaninnovativemethodtoattenuateprimarydysmenorrheaarandomizeddoubleblindclinicaltrial |
_version_ |
1724463022782545920 |