The Dragon’s Paralysing Spell: Evidence of Sodium and Calcium Ion Channel Binding Neurotoxins in Helodermatid and Varanid Lizard Venoms

The Dragon’s Paralysing Spell: Evidence of Sodium and Calcium Ion Channel Binding Neurotoxins in Helodermatid and Varanid Lizard Venoms

Bites from helodermatid lizards can cause pain, paresthesia, paralysis, and tachycardia, as well as other symptoms consistent with neurotoxicity. Furthermore, in vitro studies have shown that <i>Heloderma horridum</i> venom inhibits ion flux and blocks the electrical stimulation of skele...

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Bibliographic Details
Main Authors: James S. Dobson, Richard J. Harris, Christina N. Zdenek, Tam Huynh, Wayne C. Hodgson, Frank Bosmans, Rudy Fourmy, Aude Violette, Bryan G. Fry
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Toxins
Subjects:
<i>Heloderma</i>
<i>Varanus</i>
venom
Toxicofera
neurotoxic
sodium channel
Online Access:https://www.mdpi.com/2072-6651/13/8/549

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