Upregulation of Potassium Voltage-Gated Channel Subfamily J Member 2 Levels in the Lungs of Patients with Idiopathic Pulmonary Fibrosis

Background. Fibroblast dysfunction is the main pathogenic mechanism underpinning idiopathic pulmonary fibrosis (IPF). Potassium voltage-gated channel subfamily J member 2 (KCNJ2) plays critical roles in the proliferation of myofibroblasts and in the development of cardiac fibrosis. Objectives. This...

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Bibliographic Details
Main Authors: Jong-Uk Lee, Hun Soo Chang, Chang An Jung, Ryun Hee Kim, Choon-Sik Park, Jong-Sook Park
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2020/3406530