Combination of Selective Immunoassays and Mass Spectrometry to Characterize Preproghrelin-Derived Peptides in Mouse Tissues

Combination of Selective Immunoassays and Mass Spectrometry to Characterize Preproghrelin-Derived Peptides in Mouse Tissues

Preproghrelin is a prohormone producing several preproghrelin-derived peptides with structural and functional heterogeneity: acyl ghrelin (AG), desacyl ghrelin (DAG), and obestatin. The absence of selective and reliable assays to measure these peptides simultaneously in biological samples has been a...

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Bibliographic Details
Main Authors:	Virginie Tolle, Rim Hassouna, Dominique Grouselle, Giovanni Chiappetta, Joanna Lipecka, Oriane Fiquet, Catherine Tomasetto, Joëlle Vinh, Jacques Epelbaum
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-04-01
Series:	Frontiers in Neuroscience
Subjects:	acyl ghrelin desacyl ghrelin obestatin immunoreactivity mass spectrometry
Online Access:	http://journal.frontiersin.org/article/10.3389/fnins.2017.00211/full

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