Interleukin(IL)-36α and IL-36γ Induce Proinflammatory Mediators from Human Colonic Subepithelial Myofibroblasts

Interleukin(IL)-36α and IL-36γ Induce Proinflammatory Mediators from Human Colonic Subepithelial Myofibroblasts

Background: Interleukin (IL)-36 cytokines are recently reported member of the IL-1 cytokine family. However, there is little information regarding the association between IL-36 cytokines and gut inflammation. In the present study, we investigated the biological activity of IL-36α and IL-36γ using hu...

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Bibliographic Details
Main Authors: Toshihiro eKanda, Atsushi eNishida, Kenichiro eTakahashi, Kentaro eHidaka, Hirotsugu eImaeda, Osamu eInatomi, Shigeki eBamba, Mitsushige eSugimoto, Akira eAndoh
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Medicine
Subjects:
Colon
Interleukin-1
Myofibroblasts
inflammatory bowel diseases (IBD)
interleukin-36
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00069/full

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