miR-218 Inhibits Erythroid Differentiation and Alters Iron Metabolism by Targeting ALAS2 in K562 Cells

miR-218 Inhibits Erythroid Differentiation and Alters Iron Metabolism by Targeting ALAS2 in K562 Cells

microRNAs (miRNAs) are involved in a variety of biological processes. The regulatory function and potential role of miRNAs targeting the mRNA of the 5′-aminolevulinate synthase 2 (ALAS2) in erythropoiesis were investigated in order to identify miRNAs which play a role in erythroid iron metabolism an...

Full description

Bibliographic Details
Main Authors: Yanming Li, Shuge Liu, Hongying Sun, Yadong Yang, Heyuan Qi, Nan Ding, Jiawen Zheng, Xunong Dong, Hongzhu Qu, Zhaojun Zhang, Xiangdong Fang
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:International Journal of Molecular Sciences
Subjects:
miR-218
ALAS2
erythroid differentiation
iron metabolism
Online Access:http://www.mdpi.com/1422-0067/16/12/26088

Similar Items

Similar Items