Acoustic Radiation Force Impulse Elastography for Efficacy Evaluation after Hepatocellular Carcinoma Radiofrequency Ablation: A Comparative Study with Contrast-Enhanced Ultrasound
Aim. To explore acoustic radiation force impulse (ARFI) elastography in assessing residual tumors of hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA). Materials and Methods. There were 83 HCC lesions among 72 patients. All patients were examined with ARFI, contrast enhanced ultraso...
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2014-01-01
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doaj-f351c4c0e3064c189db7a3dd33da19b72020-11-25T00:06:39ZengHindawi LimitedBioMed Research International2314-61332314-61412014-01-01201410.1155/2014/901642901642Acoustic Radiation Force Impulse Elastography for Efficacy Evaluation after Hepatocellular Carcinoma Radiofrequency Ablation: A Comparative Study with Contrast-Enhanced UltrasoundXiaohong Xu0Liangping Luo1Jiexin Chen2Jiexin Wang3Honglian Zhou4Mingyi Li5Zhanqiang Jin6Nianping Chen7Huilai Miao8Manzhou Lin9Wei Dai10Anil T. Ahuja11Yi-Xiang J. Wang12The First Affiliated Hospital of Jinan University, Guangzhou 510632, ChinaThe First Affiliated Hospital of Jinan University, Guangzhou 510632, ChinaThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, ChinaThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, ChinaThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, ChinaThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, ChinaThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, ChinaThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, ChinaThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, ChinaThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, ChinaThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, ChinaDepartment of Imaging & Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong KongDepartment of Imaging & Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong KongAim. To explore acoustic radiation force impulse (ARFI) elastography in assessing residual tumors of hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA). Materials and Methods. There were 83 HCC lesions among 72 patients. All patients were examined with ARFI, contrast enhanced ultrasound (CEUS), and CT or MRI. Tumor brightness on virtual touch tissue imaging (VTI) and shear wave velocity (SWV) were assessed before and approximately one month after RFA. Results. There were 14 residual tumors after RFA. VTI showed that all the tumors were darker after RFA. VTI was not able to distinguish the ablated lesions and the residual tumors. 13 residual tumor lesions were detected by CEUS. All completely ablated nodules had SWV demonstration of x.xx., while with those residual nodules, 6 tumors had x.xx measurement and 8 tumors had measurable SWV. nine lesions with residual tumors occurred in cirrhosis subjects and 5 lesions with residual tumors occurred in fibrosis subjects; there was no residual tumor in the normal liver subjects. Conclusion. VTI technique cannot demonstrate residual tumor post RFA. While SWV measurement of less than x.xx is likely associated with residual tumors, measurement of less than x.xx cannot exclude residual tumors. Liver cirrhosis is associated with decreased chance of a complete ablation.http://dx.doi.org/10.1155/2014/901642 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xiaohong Xu Liangping Luo Jiexin Chen Jiexin Wang Honglian Zhou Mingyi Li Zhanqiang Jin Nianping Chen Huilai Miao Manzhou Lin Wei Dai Anil T. Ahuja Yi-Xiang J. Wang |
spellingShingle |
Xiaohong Xu Liangping Luo Jiexin Chen Jiexin Wang Honglian Zhou Mingyi Li Zhanqiang Jin Nianping Chen Huilai Miao Manzhou Lin Wei Dai Anil T. Ahuja Yi-Xiang J. Wang Acoustic Radiation Force Impulse Elastography for Efficacy Evaluation after Hepatocellular Carcinoma Radiofrequency Ablation: A Comparative Study with Contrast-Enhanced Ultrasound BioMed Research International |
author_facet |
Xiaohong Xu Liangping Luo Jiexin Chen Jiexin Wang Honglian Zhou Mingyi Li Zhanqiang Jin Nianping Chen Huilai Miao Manzhou Lin Wei Dai Anil T. Ahuja Yi-Xiang J. Wang |
author_sort |
Xiaohong Xu |
title |
Acoustic Radiation Force Impulse Elastography for Efficacy Evaluation after Hepatocellular Carcinoma Radiofrequency Ablation: A Comparative Study with Contrast-Enhanced Ultrasound |
title_short |
Acoustic Radiation Force Impulse Elastography for Efficacy Evaluation after Hepatocellular Carcinoma Radiofrequency Ablation: A Comparative Study with Contrast-Enhanced Ultrasound |
title_full |
Acoustic Radiation Force Impulse Elastography for Efficacy Evaluation after Hepatocellular Carcinoma Radiofrequency Ablation: A Comparative Study with Contrast-Enhanced Ultrasound |
title_fullStr |
Acoustic Radiation Force Impulse Elastography for Efficacy Evaluation after Hepatocellular Carcinoma Radiofrequency Ablation: A Comparative Study with Contrast-Enhanced Ultrasound |
title_full_unstemmed |
Acoustic Radiation Force Impulse Elastography for Efficacy Evaluation after Hepatocellular Carcinoma Radiofrequency Ablation: A Comparative Study with Contrast-Enhanced Ultrasound |
title_sort |
acoustic radiation force impulse elastography for efficacy evaluation after hepatocellular carcinoma radiofrequency ablation: a comparative study with contrast-enhanced ultrasound |
publisher |
Hindawi Limited |
series |
BioMed Research International |
issn |
2314-6133 2314-6141 |
publishDate |
2014-01-01 |
description |
Aim. To explore acoustic radiation force impulse (ARFI) elastography in assessing residual tumors of hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA). Materials and Methods. There were 83 HCC lesions among 72 patients. All patients were examined with ARFI, contrast enhanced ultrasound (CEUS), and CT or MRI. Tumor brightness on virtual touch tissue imaging (VTI) and shear wave velocity (SWV) were assessed before and approximately one month after RFA. Results. There were 14 residual tumors after RFA. VTI showed that all the tumors were darker after RFA. VTI was not able to distinguish the ablated lesions and the residual tumors. 13 residual tumor lesions were detected by CEUS. All completely ablated nodules had SWV demonstration of x.xx., while with those residual nodules, 6 tumors had x.xx measurement and 8 tumors had measurable SWV. nine lesions with residual tumors occurred in cirrhosis subjects and 5 lesions with residual tumors occurred in fibrosis subjects; there was no residual tumor in the normal liver subjects. Conclusion. VTI technique cannot demonstrate residual tumor post RFA. While SWV measurement of less than x.xx is likely associated with residual tumors, measurement of less than x.xx cannot exclude residual tumors. Liver cirrhosis is associated with decreased chance of a complete ablation. |
url |
http://dx.doi.org/10.1155/2014/901642 |
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