Effect of spirometry on intra-thoracic pressures

• Main Authors: Nicholas B. Tiller, Andrew J. Simpson
• Format: Article
• Language: English
• Published: BMC 2018-02-01
• Series: BMC Research Notes
• Subjects: Spirometry; Pressure; intra-thoracic pressure; Pulmonary function; Lung function; Balloon catheter
• Online Access: http://link.springer.com/article/10.1186/s13104-018-3217-9

Abstract Objective Due to the high intra-thoracic pressures associated with forced vital capacity manoeuvres, spirometry is contraindicated for vulnerable patients. However, the typical pressure response to spirometry has not been reported. Eight healthy, recreationally-active men performed spirometry while oesophageal pressure was recorded using a latex balloon-tipped catheter. Results Peak oesophageal pressure during inspiration was − 47 ± 9 cmH2O (37 ± 10% of maximal inspiratory pressure), while peak oesophageal pressure during forced expiration was 102 ± 34 cmH2O (75 ± 17% of maximal expiratory pressure). The deleterious consequences of spirometry might be associated with intra-thoracic pressures that approach maximal values during forced expiration.