Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process
A series of five novel bis-1,5-disubstituted-1H-tetrazoles (bis-1,5-DS-1H-T) were quickly prepared by a catalyst-free Ugi-azide repetitive process from easily accessible starting materials in excellent yields, either at room temperature (88%–95%) or using mild MW-heating conditions (80%–91%). These...
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MDPI AG
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/20/1/1519 |
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doaj-f378be78b0c34fb08ae82bdae96f96f82020-11-24T23:15:29ZengMDPI AGMolecules1420-30492015-01-012011519152610.3390/molecules20011519molecules20011519Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive ProcessLuís E. Cárdenas-Galindo0Alejandro Islas-Jácome1Karla M. Colmenero-Martínez2Antonio Martínez-Richa3Rocío Gámez-Montaño4Departamento Química Área Ambiental, Universidad Tecnológica de Salamanca, Av. Universidad Tecnológica No. 200, Col. Ciudad Bajío, Salamanca C.P. 36750, Gto., MexicoDepartamento de Química, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, Col. Noria Alta, Guanajuato C.P. 36050, Gto., MexicoDepartamento de Química, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, Col. Noria Alta, Guanajuato C.P. 36050, Gto., MexicoDepartamento de Química, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, Col. Noria Alta, Guanajuato C.P. 36050, Gto., MexicoDepartamento de Química, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, Col. Noria Alta, Guanajuato C.P. 36050, Gto., MexicoA series of five novel bis-1,5-disubstituted-1H-tetrazoles (bis-1,5-DS-1H-T) were quickly prepared by a catalyst-free Ugi-azide repetitive process from easily accessible starting materials in excellent yields, either at room temperature (88%–95%) or using mild MW-heating conditions (80%–91%). These molecules may have a wide range of applications, such as chelating agents, organocatalysts and luminescent materials, and mainly as bioactive compounds.http://www.mdpi.com/1420-3049/20/1/1519bis-1,5-disubstituted-1H-tetrazolesUgi-azide repetitive reactionMW-assisted synthesiscatalyst-freechelating agents |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Luís E. Cárdenas-Galindo Alejandro Islas-Jácome Karla M. Colmenero-Martínez Antonio Martínez-Richa Rocío Gámez-Montaño |
| spellingShingle |
Luís E. Cárdenas-Galindo Alejandro Islas-Jácome Karla M. Colmenero-Martínez Antonio Martínez-Richa Rocío Gámez-Montaño Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process Molecules bis-1,5-disubstituted-1H-tetrazoles Ugi-azide repetitive reaction MW-assisted synthesis catalyst-free chelating agents |
| author_facet |
Luís E. Cárdenas-Galindo Alejandro Islas-Jácome Karla M. Colmenero-Martínez Antonio Martínez-Richa Rocío Gámez-Montaño |
| author_sort |
Luís E. Cárdenas-Galindo |
| title |
Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process |
| title_short |
Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process |
| title_full |
Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process |
| title_fullStr |
Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process |
| title_full_unstemmed |
Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process |
| title_sort |
synthesis of novel bis-1,5-disubstituted-1h-tetrazoles by an efficient catalyst-free ugi-azide repetitive process |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2015-01-01 |
| description |
A series of five novel bis-1,5-disubstituted-1H-tetrazoles (bis-1,5-DS-1H-T) were quickly prepared by a catalyst-free Ugi-azide repetitive process from easily accessible starting materials in excellent yields, either at room temperature (88%–95%) or using mild MW-heating conditions (80%–91%). These molecules may have a wide range of applications, such as chelating agents, organocatalysts and luminescent materials, and mainly as bioactive compounds. |
| topic |
bis-1,5-disubstituted-1H-tetrazoles Ugi-azide repetitive reaction MW-assisted synthesis catalyst-free chelating agents |
| url |
http://www.mdpi.com/1420-3049/20/1/1519 |
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