Method development and characterisation of the low-molecular-weight peptidome of human wound fluids

Method development and characterisation of the low-molecular-weight peptidome of human wound fluids

The normal wound healing process is characterised by proteolytic events, whereas infection results in dysfunctional activations by endogenous and bacterial proteases. Peptides, downstream reporters of these proteolytic actions, could therefore serve as a promising tool for diagnosis of wounds. Using...

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Bibliographic Details
Main Authors: Mariena JA van der Plas, Jun Cai, Jitka Petrlova, Karim Saleh, Sven Kjellström, Artur Schmidtchen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
peptidomics
wound fluid
plasma
bacterial infection
peptide profiles
biomarkers
Online Access:https://elifesciences.org/articles/66876

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