Down-regulated long non-coding RNA PVT1 contributes to gestational diabetes mellitus and preeclampsia via regulation of human trophoblast cells

Down-regulated long non-coding RNA PVT1 contributes to gestational diabetes mellitus and preeclampsia via regulation of human trophoblast cells

Objective: We aimed to explore the expression level and biological function of lncRNA PVT1 in human trophoblast cells. Methods: The expression levels of PVT1 in cancer cell lines, HTR8/SVneo cell, HUVEC cell, the maternal placenta of GDM patients, PE patients and normal pregnancy were detected by qR...

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Bibliographic Details
Main Authors: Qiuhong Wang, Xun Lu, Chunyan Li, Wen Zhang, Yan Lv, Luyao Wang, Lan Wu, Li Meng, Yuru Fan, Hongjuan Ding, Wei Long, Mingming Lv
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Gestational diabetes mellitus
Preeclampsia
PVT1
lncRNA
Trophoblast cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219326113

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