3-bromopyruvate and buthionine sulfoximine effectively kill anoikis-resistant hepatocellular carcinoma cells.
Acquisition of anoikis resistance is a prerequisite for metastasis in hepatocellular carcinoma (HCC). However, little is known about how energy metabolism and antioxidant systems are altered in anoikis-resistant (AR) HCC cells. We evaluated anti-tumor effects of a combination treatment of 3-bromopyr...
Main Authors: | Minjong Lee, Ara Jo, Seulki Lee, Jong Bin Kim, Young Chang, Joon Yeul Nam, Hyeki Cho, Young Youn Cho, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Jung-Hwan Yoon, Yoon Jun Kim |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5376082?pdf=render |
Similar Items
-
The responses of Ht22 cells to oxidative stress induced by buthionine sulfoximine (BSO)
by: Berry Marla J, et al.
Published: (2005-02-01) -
Radiosensitizing glioblastoma in a rat model using l-buthionine-sr-sulfoximine (BSO)
by: Ataelmannan, Khalid Ali
Published: (2008) -
Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi.
by: JUAN DIEGO MAYA, et al.
Published: (2004-01-01) -
Correction to: Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis
by: Joan S. Lewis-Wambi, et al.
Published: (2018-06-01) -
Protective Effect of Tempol on Buthionine Sulfoximine-Induced Mitochondrial Impairment in Hippocampal Derived HT22 Cells
by: Ankita Salvi, et al.
Published: (2016-01-01)