Sectoral activation of glia in an inducible mouse model of autosomal dominant retinitis pigmentosa
Abstract Retinitis pigmentosa (RP) is a group of blinding disorders caused by diverse mutations, including in rhodopsin (RHO). Effective therapies have yet to be discovered. The I307N Rho mouse is a light-inducible model of autosomal dominant RP. Our purpose was to describe the glial response in thi...
Main Authors: | Michael T. Massengill, Neil F. Ash, Brianna M. Young, Cristhian J. Ildefonso, Alfred S. Lewin |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-73749-y |
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