Time- and Dose-Dependent Effects of 17 Beta-Estradiol on Short-Term, Real-Time Proliferation and Gene Expression in Porcine Granulosa Cells

The key mechanisms responsible for achievement of full reproductive and developmental capability in mammals are the differentiation and transformation of granulosa cells (GCs) during folliculogenesis, oogenesis, and oocyte maturation. Although the role of 17 beta-estradiol (E2) in ovarian activity i...

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Main Authors: Sylwia Ciesiółka, Joanna Budna, Karol Jopek, Artur Bryja, Wiesława Kranc, Sylwia Borys, Michal Jeseta, Adrian Chachuła, Agnieszka Ziółkowska, Paweł Antosik, Dorota Bukowska, Klaus P. Brüssow, Małgorzata Bruska, Michał Nowicki, Maciej Zabel, Bartosz Kempisty
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/9738640