The apolipoprotein E (APOE) gene appears functionally monomorphic in chimpanzees (Pan troglodytes).
<h4>Background</h4>The human apolipoprotein E (APOE) gene is polymorphic, with three primary alleles (E2, E3, E4) that differ at two key non-synonymous sites. These alleles are functionally different in how they bind to lipoproteins, and this genetic variation is associated with phenotyp...
Main Authors: | Annick M McIntosh, Calvin Bennett, Dara Dickson, Stephanie F Anestis, David P Watts, Timothy H Webster, M Babette Fontenot, Brenda J Bradley |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23112842/pdf/?tool=EBI |
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