REGIONAL EXPERIENCE OF CERVICAL CANCER PREVENTION IN THE REPUBLIC OF SAKHA (YAKUTIA)

• Main Authors: L. N. Afanaseva, M. E. Ignateva, L. V. Lyalina, N. V. Savvina, V. D. Smetanina
• Format: Article
• Language: Russian
• Published: Sankt-Peterburg : NIIÈM imeni Pastera 2014-07-01
• Series: Infekciâ i Immunitet
• Subjects: cervical cancer; hpv; one-year mortality; vaccination
• Online Access: https://www.iimmun.ru/iimm/article/view/163

Abstract. There are evidences of increasing cervix uteri malignant tumors in the Republic of Sakha (Yakutia) in the period of 2003–2013. In such situation new, more effective, but less expensive organizational measures for prevention and early identification of oncological diseases should be developed. The recent epidemiological studies have convincingly shown that high-oncological-risk genital papilloma viral infection was certain risk factor of developing pre-cancer changes and cervical cancer. Detection of HPV regional epidemiological characteristics is extremely important for optimization of programs on diagnostics and prevention of cervix uteri cancer. The epidemiological and molecular-biological studies in Yakutia have detected more high infection rate in the female population than in male one. It was established that 11 high-oncological-risks genotypes of the virus circulating in the region with considerable prevalence of HPV Type 16. Since 2008 the program on vaccination against papilloma viral infection for girls and young women aged 10 to 25 years has been implemented in Yakutia Over six years, the number of vaccinated girls and women in Yakutsk reached 1093 persons. It has been the first experience in the Siberian and Far Eastern Federal Regions.