Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating gene expression. The majority of miRNAs are transcribed from DNA sequences into primary miRNAs and processed into precursor miRNAs, and finally mature miRNAs. In most cases, miRNAs interact with the 3′ untransl...

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Bibliographic Details
Main Authors: Jacob O'Brien, Heyam Hayder, Yara Zayed, Chun Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00402/full