Efficient TALEN construction for Bombyx mori gene targeting.
Engineered nucleases are artificial enzymes able to introduce double stranded breaks at desired genomic locations. The double stranded breaks start the error-prone repair process of non-homologous end-joining (NHEJ), which eventually leads to the induction of mutations at target sites. We showed ear...
Main Authors: | Yoko Takasu, Suresh Sajwan, Takaaki Daimon, Mizuko Osanai-Futahashi, Keiro Uchino, Hideki Sezutsu, Toshiki Tamura, Michal Zurovec |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3776831?pdf=render |
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