A Versatile Axle for the Construction of Disassemblage Rotaxanes
Rotaxanes are unique mechanical devices that hold great promise as sensors. We report on two new rotaxanes that contain an acid or base sensitive trigger and readily disassemble in a wide range of environments. Disassemblage was observed under TLC and 1H-NMR analysis. The axle is highly charged, whi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2016-08-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/21/8/1043 |
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doaj-f42619a0688444e7b77111d8aca9cccc2020-11-25T00:35:48ZengMDPI AGMolecules1420-30492016-08-01218104310.3390/molecules21081043molecules21081043A Versatile Axle for the Construction of Disassemblage RotaxanesLucas A. Powers0David B. Smithrud1Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USADepartment of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USARotaxanes are unique mechanical devices that hold great promise as sensors. We report on two new rotaxanes that contain an acid or base sensitive trigger and readily disassemble in a wide range of environments. Disassemblage was observed under TLC and 1H-NMR analysis. The axle is highly charged, which enhances solubility in aqueous environments, and can be readily derivatized with sensor components. The trigger was swapped in a one-pot method, which is promising for the rapid production of a series of sensors.http://www.mdpi.com/1420-3049/21/8/1043rotaxanesdisassembleswitchpH |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Lucas A. Powers David B. Smithrud |
| spellingShingle |
Lucas A. Powers David B. Smithrud A Versatile Axle for the Construction of Disassemblage Rotaxanes Molecules rotaxanes disassemble switch pH |
| author_facet |
Lucas A. Powers David B. Smithrud |
| author_sort |
Lucas A. Powers |
| title |
A Versatile Axle for the Construction of Disassemblage Rotaxanes |
| title_short |
A Versatile Axle for the Construction of Disassemblage Rotaxanes |
| title_full |
A Versatile Axle for the Construction of Disassemblage Rotaxanes |
| title_fullStr |
A Versatile Axle for the Construction of Disassemblage Rotaxanes |
| title_full_unstemmed |
A Versatile Axle for the Construction of Disassemblage Rotaxanes |
| title_sort |
versatile axle for the construction of disassemblage rotaxanes |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2016-08-01 |
| description |
Rotaxanes are unique mechanical devices that hold great promise as sensors. We report on two new rotaxanes that contain an acid or base sensitive trigger and readily disassemble in a wide range of environments. Disassemblage was observed under TLC and 1H-NMR analysis. The axle is highly charged, which enhances solubility in aqueous environments, and can be readily derivatized with sensor components. The trigger was swapped in a one-pot method, which is promising for the rapid production of a series of sensors. |
| topic |
rotaxanes disassemble switch pH |
| url |
http://www.mdpi.com/1420-3049/21/8/1043 |
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AT lucasapowers aversatileaxlefortheconstructionofdisassemblagerotaxanes AT davidbsmithrud aversatileaxlefortheconstructionofdisassemblagerotaxanes AT lucasapowers versatileaxlefortheconstructionofdisassemblagerotaxanes AT davidbsmithrud versatileaxlefortheconstructionofdisassemblagerotaxanes |
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