Anti-Inflammatory Effects and Mechanisms of Action of Coussaric and Betulinic Acids Isolated from Diospyros kaki in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

Anti-Inflammatory Effects and Mechanisms of Action of Coussaric and Betulinic Acids Isolated from Diospyros kaki in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

Diospyros kaki Thunb. is widely distributed in East Asian countries, its leaves being mainly used for making tea. In this study, coussaric acid (CA) and betulinic acid (BA), both triterpenoid compounds, were obtained from D. kaki leaf extracts through bioassay-guided isolation. CA and BA showed anti...

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Bibliographic Details
Main Authors: Kyoung-Su Kim, Dong-Sung Lee, Dong-Cheol Kim, Chi-Su Yoon, Wonmin Ko, Hyuncheol Oh, Youn-Chul Kim
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Molecules
Subjects:
Diospyros kaki Thunb.
coussaric acid (CA)
betulinic acid (BA)
anti-inflammation
nuclear factor-kappa B
heme oxygenase-1
Online Access:http://www.mdpi.com/1420-3049/21/9/1206

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