Effects of polymorphic cytochrome P450 2A6 genotypes on chemoprevention against colorectal tumors in single Japanese cohort using daily low-dose aspirin: insights into future personalized treatments

Effects of polymorphic cytochrome P450 2A6 genotypes on chemoprevention against colorectal tumors in single Japanese cohort using daily low-dose aspirin: insights into future personalized treatments

Abstract Background A chemopreventive effect of low-dose aspirin against colorectal tumors was previously found in participants of two Japanese multicenter, double-blind, randomized, placebo-controlled clinical trials investigating the effects of daily aspirin (100 mg/day) for 0.7–2 years on tumor r...

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Bibliographic Details
Main Authors: Hiroshi Yamazaki, Makiko Shimizu, Takahiro Otani, Ami Mizugaki, Kanae Mure, Sadao Suzuki, Hideki Ishikawa
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
CYP2A6
Acetylsalicylic acid
Chemoprevention
Ethnic difference
Online Access:https://doi.org/10.1186/s40780-021-00209-8

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