Prediction of human disease genes by human-mouse conserved coexpression analysis.

BACKGROUND: Even in the post-genomic era, the identification of candidate genes within loci associated with human genetic diseases is a very demanding task, because the critical region may typically contain hundreds of positional candidates. Since genes implicated in similar phenotypes tend to share...

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Bibliographic Details
Main Authors: Ugo Ala, Rosario Michael Piro, Elena Grassi, Christian Damasco, Lorenzo Silengo, Martin Oti, Paolo Provero, Ferdinando Di Cunto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2268251?pdf=render