Ergosterol peroxide isolated from Ganoderma lucidum abolishes microRNA miR-378-mediated tumor cells on chemoresistance.
Due to an altered expression of oncogenic factors and tumor suppressors, aggressive cancer cells have an intrinsic or acquired resistance to chemotherapeutic agents. This typically contributes to cancer recurrence after chemotherapy. microRNAs are short non-coding RNAs that are involved in both cell...
Main Authors: | Qing-Ping Wu, Yi-Zhen Xie, Zhaoqun Deng, Xiang-Min Li, Weining Yang, Chun-Wei Jiao, Ling Fang, Sen-Zhu Li, Hong-Hui Pan, Albert J Yee, Daniel Y Lee, Chong Li, Zhi Zhang, Jun Guo, Burton B Yang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3431381?pdf=render |
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