Telomeres as Therapeutic Targets in Heart Disease

Summary: Telomeres are double-stranded repeats of G-rich tandem DNA sequences that gradually shorten with each cell division. Aging, inflammation, and oxidative stress accelerate the process of telomere shortening. Telomerase counteracts this process by maintaining and elongating the telomere length...

Full description

Bibliographic Details
Main Authors: Jih-Kai Yeh, MD, Mei-Hsiu Lin, MS, Chao-Yung Wang, MD
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X19301779

Similar Items