The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells
γδ T cells contribute to first line immune defense, particularly through their ability for rapid production of proinflammatory cytokines. The cytokine profile of γδ T cells is hard-wired already during thymic development. Yet, the molecular pathways underlying this phenomenon are incompletely unders...
Main Authors: | Florian Mair, Stefanie Joller, Romy Hoeppli, Lucas Onder, Matthias Hahn, Burkhard Ludewig, Ari Waisman, Burkhard Becher |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/10087 |
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