Acute sleep deprivation enhances susceptibility to the migraine substrate cortical spreading depolarization

Acute sleep deprivation enhances susceptibility to the migraine substrate cortical spreading depolarization

Abstract Background Migraine is a common headache disorder, with cortical spreading depolarization (CSD) considered as the underlying electrophysiological event. CSD is a slowly propagating wave of neuronal and glial depolarization. Sleep disorders are well known risk factors for migraine chronifica...

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Bibliographic Details
Main Authors: Andrea Negro, Jessica L. Seidel, Thijs Houben, Esther S. Yu, Ike Rosen, Andrea J. Arreguin, Nilufer Yalcin, Lea Shorser-Gentile, Lea Pearlman, Homa Sadhegian, Ramalingam Vetrivelan, Nancy L. Chamberlin, Cenk Ayata, Paolo Martelletti, Michael A. Moskowitz, Katharina Eikermann-Haerter
Format: Article
Language:English
Published: BMC 2020-07-01
Series:The Journal of Headache and Pain
Subjects:
Cortical spreading depolarization
CSD
Migraine
Sleep deprivation
Ventrolateral preoptic (VLPO) nucleus
VLPO
Online Access:http://link.springer.com/article/10.1186/s10194-020-01155-w

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