Antioxidative 1,4-Dihydropyridine Derivatives Modulate Oxidative Stress and Growth of Human Osteoblast-Like Cells In Vitro

Antioxidative 1,4-Dihydropyridine Derivatives Modulate Oxidative Stress and Growth of Human Osteoblast-Like Cells In Vitro

Oxidative stress has been implicated in pathophysiology of different human stress- and age-associated disorders, including osteoporosis for which antioxidants could be considered as therapeutic remedies as was suggested recently. The 1,4-dihydropyridine (DHP) derivatives are known for their pleiotro...

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Bibliographic Details
Main Authors: Lidija Milkovic, Tea Vukovic, Neven Zarkovic, Franz Tatzber, Egils Bisenieks, Zenta Kalme, Imanta Bruvere, Zaiga Ogle, Janis Poikans, Astrida Velena, Gunars Duburs
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Antioxidants
Subjects:
1,4-dihydropyridine(s) (DHPs)
oxidative stress
reactive oxygen species (ROS)
antioxidant (AO)
antioxidative activity (AOA)
glutathione
cell viability and proliferation
4-hydroxynonenal (4-HNE)
Online Access:http://www.mdpi.com/2076-3921/7/9/123

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