Rolling up the pieces of a puzzle: A systematic review and meta-analysis of the prevalence of toxoplasmosis in Iran
Toxoplasmosis is a neglected parasitic disease with global distribution in warm-blooded vertebrates and high prevalence among different human societies. We contrived a systematic review and meta-analysis on the prevalence of toxoplasmosis in Iran. Following the general methodology recommended for sy...
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doaj-f4c63d419c884fb0a09039206d6f651d2021-01-02T06:54:37ZengTaylor & Francis GroupAlexandria Journal of Medicine2090-50682018-09-01543189196Rolling up the pieces of a puzzle: A systematic review and meta-analysis of the prevalence of toxoplasmosis in IranMasoud Foroutan0Sahar Dalvand1Ahmad Daryani2Ehsan Ahmadpour3Hamidreza Majidiani4Shahram Khademvatan5Esmaeil Abbasi6Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran; Student Research Committee, Urmia University of Medical Sciences, Urmia, IranClinical Care Research Center, Kurdistan University of Medical Sciences, Sanandaj, IranToxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, IranInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran; Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran; Corresponding authors.Cellular and Molecular Research Center & Department of Medical Parasitology and Mycology, Urmia University of Medical Sciences, Urmia, Iran; Corresponding authors.Student Research Committee, Urmia University of Medical Sciences, Urmia, IranToxoplasmosis is a neglected parasitic disease with global distribution in warm-blooded vertebrates and high prevalence among different human societies. We contrived a systematic review and meta-analysis on the prevalence of toxoplasmosis in Iran. Following the general methodology recommended for systematic reviews and meta-analysis, four English and three Persian electronic databases were explored up to April 2016. Out of 105,139 examined samples of different hosts, the weighted overall prevalence was 37% (95% CI = 31–43). Due to the significant heterogeneity (I2 = 81.9%) the random-effects model was used. The pool estimated prevalence of toxoplasmosis in human intermediate hosts, animal intermediate hosts, and definitive hosts was 43% (95% CI = 38–47), 26 (95% CI = 17–35) and, 34% (95% CI = 22–46), respectively. Our results represent that regular inspection in food industries, improved screening programs using standard diagnostic assay as well as distinguishing toxoplasmosis condition in other zoonotic hosts are extremely recommended for better disease management in Iran. Keywords: Toxoplasma gondii, Prevalence, Iran, Systematic review, Meta-analysishttp://www.sciencedirect.com/science/article/pii/S209050681730088X |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Masoud Foroutan Sahar Dalvand Ahmad Daryani Ehsan Ahmadpour Hamidreza Majidiani Shahram Khademvatan Esmaeil Abbasi |
spellingShingle |
Masoud Foroutan Sahar Dalvand Ahmad Daryani Ehsan Ahmadpour Hamidreza Majidiani Shahram Khademvatan Esmaeil Abbasi Rolling up the pieces of a puzzle: A systematic review and meta-analysis of the prevalence of toxoplasmosis in Iran Alexandria Journal of Medicine |
author_facet |
Masoud Foroutan Sahar Dalvand Ahmad Daryani Ehsan Ahmadpour Hamidreza Majidiani Shahram Khademvatan Esmaeil Abbasi |
author_sort |
Masoud Foroutan |
title |
Rolling up the pieces of a puzzle: A systematic review and meta-analysis of the prevalence of toxoplasmosis in Iran |
title_short |
Rolling up the pieces of a puzzle: A systematic review and meta-analysis of the prevalence of toxoplasmosis in Iran |
title_full |
Rolling up the pieces of a puzzle: A systematic review and meta-analysis of the prevalence of toxoplasmosis in Iran |
title_fullStr |
Rolling up the pieces of a puzzle: A systematic review and meta-analysis of the prevalence of toxoplasmosis in Iran |
title_full_unstemmed |
Rolling up the pieces of a puzzle: A systematic review and meta-analysis of the prevalence of toxoplasmosis in Iran |
title_sort |
rolling up the pieces of a puzzle: a systematic review and meta-analysis of the prevalence of toxoplasmosis in iran |
publisher |
Taylor & Francis Group |
series |
Alexandria Journal of Medicine |
issn |
2090-5068 |
publishDate |
2018-09-01 |
description |
Toxoplasmosis is a neglected parasitic disease with global distribution in warm-blooded vertebrates and high prevalence among different human societies. We contrived a systematic review and meta-analysis on the prevalence of toxoplasmosis in Iran. Following the general methodology recommended for systematic reviews and meta-analysis, four English and three Persian electronic databases were explored up to April 2016. Out of 105,139 examined samples of different hosts, the weighted overall prevalence was 37% (95% CI = 31–43). Due to the significant heterogeneity (I2 = 81.9%) the random-effects model was used. The pool estimated prevalence of toxoplasmosis in human intermediate hosts, animal intermediate hosts, and definitive hosts was 43% (95% CI = 38–47), 26 (95% CI = 17–35) and, 34% (95% CI = 22–46), respectively. Our results represent that regular inspection in food industries, improved screening programs using standard diagnostic assay as well as distinguishing toxoplasmosis condition in other zoonotic hosts are extremely recommended for better disease management in Iran. Keywords: Toxoplasma gondii, Prevalence, Iran, Systematic review, Meta-analysis |
url |
http://www.sciencedirect.com/science/article/pii/S209050681730088X |
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