Quantitative multiplex profiling of the complement system to diagnose complement‐mediated diseases

Quantitative multiplex profiling of the complement system to diagnose complement‐mediated diseases

Abstract Objectives Complement deficiencies are difficult to diagnose because of the variability of symptoms and the complexity of the diagnostic process. Here, we applied a novel ‘complementomics’ approach to study the impact of various complement deficiencies on circulating complement levels. Meth...

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Bibliographic Details
Main Authors: Esther Willems, Laura Lorés‐Motta, Andrea Zanichelli, Chiara Suffritti, Michiel van derFlier, Renate G van derMolen, Jeroen D Langereis, Joris vanDrongelen, Lambert P van denHeuvel, Elena Volokhina, Nicole CAJ van deKar, Jenneke Keizer‐Garritsen, Michael Levin, Jethro A Herberg, Federico Martinon‐Torres, Hans JTC Wessels, Anita deBreuk, Sascha Fauser, Carel B Hoyng, Anneke I denHollander, Ronald deGroot, Alain J vanGool, Jolein Gloerich, Marien I deJonge
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical & Translational Immunology
Subjects:
complement deficiencies
complement system
complement‐mediated diseases
complementomics
multiplex targeted mass spectrometry
pathway analysis
Online Access:https://doi.org/10.1002/cti2.1225

Internet

https://doi.org/10.1002/cti2.1225

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