Oncoprotein LAMTOR5 activates GLUT1 via upregulating NF-κB in liver cancer

Accumulating reports reveal that serving as an oncogenic factor LAMTOR5 is involved in the progression of many specific cancers. Glucose transporter 1 (GLUT1) is frequently identified in many cancers. However, it remains unexplored whether GLUT1 plays a role in LAMTOR5-enhanced liver cancer. Here, w...

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Bibliographic Details
Main Authors: Zhou Jing, Li Yajun, Li Danhua, Liu Zhi, Zhang Jie
Format: Article
Language:English
Published: De Gruyter 2019-02-01
Series:Open Medicine
Subjects:
Online Access:http://www.degruyter.com/view/j/med.2019.14.issue-1/med-2019-0022/med-2019-0022.xml?format=INT
Description
Summary:Accumulating reports reveal that serving as an oncogenic factor LAMTOR5 is involved in the progression of many specific cancers. Glucose transporter 1 (GLUT1) is frequently identified in many cancers. However, it remains unexplored whether GLUT1 plays a role in LAMTOR5-enhanced liver cancer. Here, we aim to decipher the function of LAMTOR5 in the regulation of GLUT1 in liver cancer.
ISSN:2391-5463