Current Devices in Mitral Valve Replacement and Their Potential Complications

• Main Authors: Livia Gheorghe, Jorn Brouwer, Dee Dee Wang, Nina Wunderlich, Bushra Rana, Benno Rensing, Frank Eefting, Leo Timmers, Martin Swaans
• Format: Article
• Language: English
• Published: Frontiers Media S.A. 2020-11-01
• Series: Frontiers in Cardiovascular Medicine
• Subjects: mitral valve; mitral replacement; complication; minimal invasive approach; LVOT obstruction
• Online Access: https://www.frontiersin.org/articles/10.3389/fcvm.2020.531843/full

Mitral regurgitation is one of the most prevalent valvulopathies worldwide, and its surgical treatment is not feasible in all cases. The elderly and frail with several comorbidities and left ventricular dysfunction are often managed conservatively. Percutaneous treatment (repair or replacement) of the mitral valve has emerged as a potential option for those patients who are at a high risk for surgery. Mitral valve repair with the Mitraclip device proved both increased safety and mortality reduction in patients with severe mitral regurgitation. On the other hand, in the last decade, percutaneous mitral replacement opened new frontiers in the field of cardiac structural interventions. There are few mitral devices; some are in the early phase of development and some are waiting for CE mark of approval. The evolution of these devices was more complicated compared to the aortic technology due to the native mitral valve's complexity and access. This review aims to provide an overview of the current devices, their specific features, and their potential complications.