Prevention of severe infectious complications after colorectal surgery using oral non-absorbable antimicrobial prophylaxis: results of a multicenter randomized placebo-controlled clinical trial

Prevention of severe infectious complications after colorectal surgery using oral non-absorbable antimicrobial prophylaxis: results of a multicenter randomized placebo-controlled clinical trial

Abstract Background Surgical site infections (SSIs) are common complications after colorectal surgery. Oral non-absorbable antibiotic prophylaxis (OAP) can be administered preoperatively to reduce the risk of SSIs. Its efficacy without simultaneous mechanical cleaning is unknown. Methods The Precaut...

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Main Authors: Tessa Mulder, Marjolein Kluytmans-van den Bergh, Bart Vlaminckx, Daphne Roos, Anne Marie de Smet, Robert de Vos tot Nederveen Cappel, Paul Verheijen, Alexandra Brandt, Anke Smits, Eric van der Vorm, Erik Bathoorn, Boudewijn van Etten, Jacobien Veenemans, Annemarie Weersink, Margreet Vos, Nils van ’t Veer, Stavros Nikolakopoulos, Marc Bonten, Jan Kluytmans
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Antimicrobial Resistance and Infection Control
Subjects:
Infection control
Preoperative oral antibiotic prophylaxis
Colorectal surgery
Surgical site infection
Online Access:http://link.springer.com/article/10.1186/s13756-020-00745-2

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