Aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of Schistosoma mansoni
In this study, which was undertaken in relation to the histopathologic behavior of two different strains (LE-Belo Horizonte, MG and SJ - São José dos Campos, SP) in infections and reinfections (homologous or heterologous) with Schistosoma mansoni, the authors confirmed a more accentuated pathogenici...
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Sociedade Brasileira de Medicina Tropical (SBMT)
1994-12-01
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doaj-f50b45034e4842e7ac347e803991c4e72020-11-24T22:25:06ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical0037-86821678-98491994-12-01274221226Aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of Schistosoma mansoniPedro RasoPaulo Marcos Z. CoelhoNivaldo H. ToppaRômulo T. MelloIn this study, which was undertaken in relation to the histopathologic behavior of two different strains (LE-Belo Horizonte, MG and SJ - São José dos Campos, SP) in infections and reinfections (homologous or heterologous) with Schistosoma mansoni, the authors confirmed a more accentuated pathogenicity of the SJ strain. All the reinfections showed the presence of typical granulomas of the acute phase, when performed either with the same strain (homologous) or with a different strain (heterologous) of the parasite of the primo infection. The possible mechanisms responsible for reactivation of the immunopathologic response in reinfections are discussed.<br>No presente estudo, verificou-se o comportamento histopatológico das infecções e reinfecções, homólogas ou heterólogas, das cepas LE (Belo Horizonte, MG) e SJ (São José dos Campos, SP) de Schistosoma mansoni. Confirmou-se uma maior patogenicidade da cepa SJ de S. mansoni. As reinfecções, independentemente de terem sido feitas com a mesma cepa (homóloga) ou cepa diferente da primo infecção (heteróloga) do parasito, mostraram a presença de granulomas típicos da fase aguda. São discutidos os possíveis mecanismos responsáveis pela reagudização da resposta imunopatológica nas reinfecções.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821994000400004GranulomaReação granulomatosaSchistosoma mansoniCepas geográficasGranulomaGranulomatous reactionSchistosoma mansoniGeographical strains |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pedro Raso Paulo Marcos Z. Coelho Nivaldo H. Toppa Rômulo T. Mello |
spellingShingle |
Pedro Raso Paulo Marcos Z. Coelho Nivaldo H. Toppa Rômulo T. Mello Aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of Schistosoma mansoni Revista da Sociedade Brasileira de Medicina Tropical Granuloma Reação granulomatosa Schistosoma mansoni Cepas geográficas Granuloma Granulomatous reaction Schistosoma mansoni Geographical strains |
author_facet |
Pedro Raso Paulo Marcos Z. Coelho Nivaldo H. Toppa Rômulo T. Mello |
author_sort |
Pedro Raso |
title |
Aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of Schistosoma mansoni |
title_short |
Aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of Schistosoma mansoni |
title_full |
Aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of Schistosoma mansoni |
title_fullStr |
Aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of Schistosoma mansoni |
title_full_unstemmed |
Aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of Schistosoma mansoni |
title_sort |
aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of schistosoma mansoni |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
series |
Revista da Sociedade Brasileira de Medicina Tropical |
issn |
0037-8682 1678-9849 |
publishDate |
1994-12-01 |
description |
In this study, which was undertaken in relation to the histopathologic behavior of two different strains (LE-Belo Horizonte, MG and SJ - São José dos Campos, SP) in infections and reinfections (homologous or heterologous) with Schistosoma mansoni, the authors confirmed a more accentuated pathogenicity of the SJ strain. All the reinfections showed the presence of typical granulomas of the acute phase, when performed either with the same strain (homologous) or with a different strain (heterologous) of the parasite of the primo infection. The possible mechanisms responsible for reactivation of the immunopathologic response in reinfections are discussed.<br>No presente estudo, verificou-se o comportamento histopatológico das infecções e reinfecções, homólogas ou heterólogas, das cepas LE (Belo Horizonte, MG) e SJ (São José dos Campos, SP) de Schistosoma mansoni. Confirmou-se uma maior patogenicidade da cepa SJ de S. mansoni. As reinfecções, independentemente de terem sido feitas com a mesma cepa (homóloga) ou cepa diferente da primo infecção (heteróloga) do parasito, mostraram a presença de granulomas típicos da fase aguda. São discutidos os possíveis mecanismos responsáveis pela reagudização da resposta imunopatológica nas reinfecções. |
topic |
Granuloma Reação granulomatosa Schistosoma mansoni Cepas geográficas Granuloma Granulomatous reaction Schistosoma mansoni Geographical strains |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821994000400004 |
work_keys_str_mv |
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