Identification of the iduronate-2-sulfatase proteome in wild-type mouse brain

Identification of the iduronate-2-sulfatase proteome in wild-type mouse brain

Iduronate-2-sulfatase (IDS) is a lysosomal enzyme involved in the metabolism of the glycosaminoglycans heparan (HS) and dermatan (DS) sulfate. Mutations on IDS gene produce mucopolysaccharidosis II (MPS II), characterized by the lysosomal accumulation of HS and DS, leading to severe damage of the ce...

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Bibliographic Details
Main Authors: Carolina Cardona, Eliana Benincore, Natalia Pimentel, Luis H. Reyes, Camilo Patarroyo, Alexander Rodríguez-López, M. Martin-Rufian, Luis Alejandro Barrera, Carlos J. Alméciga-Díaz
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Heliyon
Subjects:
Biochemistry
Bioinformatics
Biotechnology
Cell biology
Computational biology
Online Access:http://www.sciencedirect.com/science/article/pii/S240584401931076X

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http://www.sciencedirect.com/science/article/pii/S240584401931076X

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