Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease

<p>Abstract</p> <p>Background</p> <p>Regulatory T cells (Tregs) play an essential role in the control of the immune response. Treg cells represent important targets for therapeutic interventions of the immune system. Therefore, it will be very important to understand in...

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Bibliographic Details
Main Authors: Alberts Rudi, Chen Hairong, Pommerenke Claudia, Smit August B, Spijker Sabine, Williams Robert W, Geffers Robert, Bruder Dunja, Schughart Klaus
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/12/610